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Amylase, a-, Aspergillus oryzae CAS: 9001-19-8 Tus nqi tsim khoom
Amylase yog ib qho enzyme uas pab txhawb kev rhuav tshem cov hmoov txhuv nplej siab ua cov suab thaj yooj yim xws li maltose thiab glucose. Nws feem ntau yog tsim los ntawm ntau yam kab mob, suav nrog cov kab mob me me, cov pwm, thiab cov nroj tsuag.
Tus "a-" hauv "a-amylase" txhais tau hais tias hom amylase uas hydrolyzes cov alpha-1,4 glycosidic bonds sab hauv hauv cov hmoov txhuv nplej siab. Qhov no ua rau muaj cov polysaccharides luv luv, uas tuaj yeem raug rhuav tshem mus ua glucose los ntawm lwm cov enzymes amylase.
Aspergillus oryzae yog ib hom pwm filamentous uas paub txog nws lub peev xwm los tsim cov amylase ntau. Nws feem ntau siv rau hauv cov txheej txheem tsim cov enzyme hauv kev lag luam vim nws muaj zog amylolytic. Cov enzymes uas Aspergillus oryzae tsim tawm, suav nrog a-amylase, siv dav hauv ntau yam lag luam, xws li zaub mov, brewing, textile, thiab kev tsim cov tshuaj ntxuav tes.
Hauv kev lag luam khoom noj, a-amylase uas tau los ntawm Aspergillus oryzae feem ntau siv rau hauv kev ci, ua kom sov, thiab ua cov hmoov txhuv nplej siab. Nws pab rhuav cov hmoov txhuv nplej siab hauv cov khob cij, malt, thiab lwm yam khoom siv raw, pab txhawb kev hloov pauv ntawm cov carbohydrates nyuaj mus rau hauv cov suab thaj yooj yim uas tuaj yeem metabolized los ntawm cov poov xab lossis cov kab mob thaum lub sijhawm fermentation. Cov enzyme no kuj tseem siv rau hauv kev tsim cov ntaub los pab txhawb kev tshem tawm cov tshuaj ntsuas raws li hmoov txhuv nplej siab ntawm cov ntaub.
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Aprotinin CAS: 9087-70-1 Tus nqi tsim khoom
Aprotinin yog ib yam khoom uas muaj protein ua lub luag haujlwm tiv thaiv ntau yam enzymes proteolytic, suav nrog trypsin, chymotrypsin, thiab plasmin. Nws feem ntau siv rau hauv kev kho mob, tshwj xeeb tshaj yog hauv kev phais plawv, kom txo qhov los ntshav thiab txo qhov poob ntshav. Aprotinin ua haujlwm los ntawm kev txwv tsis pub cov enzymes no ua haujlwm, uas koom nrog kev rhuav tshem cov ntshav txhaws thiab kev puas tsuaj ntawm fibrin, ib qho protein uas pab tsim cov ntshav txhaws. Los ntawm kev tiv thaiv kev ua haujlwm ntawm enzymatic ntau dhau, aprotinin pab tswj kev ruaj khov ntawm cov ntshav txhaws, yog li txo cov teeb meem los ntshav thaum phais.
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Thrombin CAS: 9002-04-4 Tus nqi tsim khoom
Thrombin yog ib qho enzyme tseem ceeb uas koom nrog kev txhaws ntshav, tseem hu ua coagulation. Nws yog tsim los ntawm nws cov protein ua ntej, prothrombin, los teb rau kev raug mob lossis kev puas tsuaj rau cov hlab ntsha. Thrombin ua lub luag haujlwm tseem ceeb hauv kev tsim cov ntshav txhaws, uas pab tiv thaiv kev los ntshav ntau dhau thiab txhawb kev kho qhov txhab.
Thaum twg thrombin ua haujlwm lawm, nws yuav hloov fibrinogen, uas yog lwm yam protein hauv cov ntshav, mus ua fibrin. Fibrin ua ib lub qauv zoo li daim ntaub uas ntes cov platelets thiab cov qe ntshav liab, ua rau cov ntshav khov kho. Thrombin kuj ua rau lwm yam coagulation factors ua haujlwm, ua rau cov txheej txheem coagulation loj zuj zus.
Tsis tas li ntawd xwb, thrombin tseem muaj lwm yam haujlwm tseem ceeb. Nws pab kom cov qhov txhab zoo los ntawm kev txhawb kom cov hlwb uas koom nrog kev kho cov nqaij mob txav mus los thiab loj hlob. Thrombin kuj ua haujlwm ua vasoconstrictor, ua rau cov hlab ntsha nqaim thiab txo cov ntshav ntws mus rau qhov chaw raug mob.
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Urease CAS: 9002-13-5 Tus nqi tsim khoom
Urease yog ib qho enzyme uas ua rau lub hydrolysis ntawm urea mus rau hauv ammonia thiab carbon dioxide. Nws yog tsim los ntawm ntau yam kab mob me me, suav nrog cov kab mob, cov pwm, thiab cov nroj tsuag. Urease yog qhov tseem ceeb rau kev ua kom cov nitrogen metabolism thiab ua lub luag haujlwm tseem ceeb hauv ntau yam txheej txheem biological, xws li urea hydrolysis hauv lub raum thiab nitrogen assimilation hauv cov nroj tsuag. Nws kuj muaj cov ntawv thov kev lag luam, suav nrog kev kuaj mob ntawm cov kab mob urease, urea-based chiv, thiab kev kuaj pom cov urease inhibitors rau kev kho mob ntawm qee yam mob.
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Leupeptin hemisulfate CAS: 103476-89-7
Leupeptin hemisulfate yog ib qho protease inhibitor uas feem ntau siv rau hauv kev tshawb fawb biochemical thiab biomedical. Nws yog muab los ntawm cov kab mob Streptomyces thiab ua haujlwm los ntawm kev txwv tsis pub ua haujlwm ntawm ntau yam proteases, suav nrog trypsin, chymotrypsin, thiab plasmin.
Leupeptin hemisulfate feem ntau siv rau hauv kev sim hauv chav kuaj kom tiv thaiv kev puas tsuaj ntawm cov protein tsis xav tau, vim tias cov proteases tuaj yeem rhuav tshem cov protein thiab peptides, cuam tshuam rau cov txiaj ntsig ntawm kev sim. Los ntawm kev txwv tsis pub ua haujlwm ntawm protease, leupeptin hemisulfate pab ua kom cov protein ruaj khov thiab tswj lawv qhov kev ua tiav thaum lub sijhawm sim.
Tsis tas li ntawd xwb, leupeptin hemisulfate tau siv rau hauv kev tshawb fawb txog kab lis kev cai ntawm tes los tshawb nrhiav lub luag haujlwm ntawm cov proteases hauv ntau yam txheej txheem ntawm tes, xws li kev xa xov ntawm tes, apoptosis, thiab kev hloov pauv protein.
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Lipase los ntawm porcine pancreas CAS: 9001-62-1
Lipase yog ib qho enzyme uas ua rau cov lipids hydrolysis, tshwj xeeb tshaj yog qhov kev rhuav tshem cov triglycerides mus rau hauv cov roj fatty acids thiab glycerol. Nws yog tsim los ntawm ntau yam kab mob, suav nrog tsiaj txhu, nroj tsuag, thiab cov kab mob me me. Lipase ua lub luag haujlwm tseem ceeb hauv kev zom zaub mov, vim nws pab hauv kev rhuav tshem thiab nqus cov rog hauv cov hnyuv me. Tsis tas li ntawd, lipase muaj ntau daim ntawv thov hauv kev lag luam xws li kev ua zaub mov, kev tsim cov tshuaj ntxuav tes, tshuaj, thiab kev tsim cov roj biofuel. Nws lub peev xwm los hydrolyze lipids ua rau nws muaj txiaj ntsig zoo rau cov haujlwm xws li kev hloov pauv lipid, kev txhim kho saj, thiab kev rho tawm roj.
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Lysostaphin CAS: 9011-93-2 Tus nqi tsim khoom
Lysostaphin yog ib qho enzyme muaj zog tua kab mob uas tua tau Staphylococcus aureus, ib hom kab mob uas ua rau muaj ntau yam kab mob hauv tib neeg. Nws yog los ntawm cov kab mob Staphylococcus simulans thiab muaj peev xwm rhuav tshem cov phab ntsa ntawm S. aureus, ua rau nws puas tsuaj.
Cov enzyme no tsom mus rau txheej peptidoglycan ntawm phab ntsa cell ntawm cov kab mob, ua rau nws cov qauv puas tsuaj thiab ua rau cov kab mob lysis. Lub tshuab ua haujlwm tshwj xeeb no ua rau lysostaphin ua haujlwm zoo tiv thaiv cov kab mob S. aureus, suav nrog cov uas tiv taus cov tshuaj tua kab mob uas siv ntau.
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L-Lactate dehydrogenase CAS: 9001-60-9
L-Lactate dehydrogenase (LDH) yog ib qho enzyme uas ua lub luag haujlwm tseem ceeb hauv kev hloov pauv lub zog ntawm lub cev, tshwj xeeb tshaj yog hauv kev hloov pauv ntawm pyruvate mus rau lactate. Nws catalyzes qhov kev hloov pauv rov qab ntawm L-lactate mus rau pyruvate, siv NAD + ua tus cofactor.
LDH pom muaj nyob rau hauv ntau yam nqaij ntawm lub cev, suav nrog lub siab, lub plawv, cov leeg, thiab cov qe ntshav liab. Nws cov qib kev ua haujlwm tuaj yeem ua lub cim kuaj mob rau qee yam kab mob, xws li kev puas tsuaj rau lub siab, myocardial infarction, thiab qee hom mob qog noj ntshav.
Lub luag haujlwm tseem ceeb ntawm LDH yog tswj kom lub zog ntawm lub cev sib npaug los ntawm kev pab hloov pauv pyruvate, ib yam khoom ntawm glycolysis, mus rau hauv lactate. Cov txheej txheem no, hu ua anaerobic glycolysis, tshwm sim thaum tsis muaj oxygen thiab tso cai rau cov hlwb txuas ntxiv tsim lub zog thaum cov pa oxygen tsawg.
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Pepsin CAS: 9001-76-7 Tus nqi tsim khoom
Pepsin yog ib qho enzyme zom zaub mov uas pom muaj nyob rau hauv lub plab uas ua lub luag haujlwm tseem ceeb hauv kev zom thiab rhuav tshem cov protein. Nws yog ib feem ntawm ib pawg ntawm cov enzymes hu ua proteases, uas yog lub luag haujlwm rau kev rhuav tshem cov protein ua cov peptides me me thiab amino acids, ua rau lawv nqus tau hauv txoj hnyuv me.
Pepsin yog tsim tawm thiab tso tawm los ntawm cov hlwb uas nyob hauv lub plab, hu ua cov hlwb tseem ceeb, hauv daim ntawv tsis ua haujlwm hu ua pepsinogen. Thaum cov khoom noj nkag mus rau hauv lub plab, nws ua rau cov kua qaub hauv plab tso tawm, uas hloov pepsinogen mus ua nws daim ntawv nquag, pepsin. Pepsin ua haujlwm zoo tshaj plaws hauv ib puag ncig acidic, vim tias pH qis ntawm lub plab pab ua kom nws cov enzymatic ua haujlwm.
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Protein Kinase Supplement KT5823 CAS: 126643-37-6
Protein kinase ntxiv KT5823 yog ib qho tshuaj me me uas tiv thaiv cov protein kinase ua haujlwm. Protein kinases yog cov enzymes uas phosphorylate cov protein los ntawm kev ntxiv cov pab pawg phosphate rau cov amino acid residues tshwj xeeb, feem ntau yog serine, threonine, lossis tyrosine. Cov txheej txheem phosphorylation no ua lub luag haujlwm tseem ceeb hauv ntau txoj kev xa xov ntawm tes, tswj cov protein ua haujlwm, thiab tswj cov txheej txheem ntawm tes xws li kev loj hlob ntawm tes, kev faib, kev sib txawv, thiab apoptosis.
KT5823 feem ntau siv rau hauv kev tshawb fawb los tshawb nrhiav kev ua haujlwm thiab cov kev taw qhia ntawm cov protein kinases. Los ntawm kev txwv cov protein kinases, KT5823 tuaj yeem pab cov kws tshawb fawb txiav txim siab cov protein tshwj xeeb thiab cov kev cuam tshuam los ntawm kev ua haujlwm kinase. Cov ntaub ntawv no tuaj yeem nkag siab txog lub luag haujlwm ntawm cov protein kinases hauv cov haujlwm ntawm tes thiab tej zaum yuav txheeb xyuas cov hom phiaj kho mob tshiab.
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Pyridoxal-5′-phosphate monohydrate CAS: 41468-25-1
Pyridoxal-5′-phosphate monohydrate, tseem hu ua PLP, yog daim ntawv nquag ntawm vitamin B6. Nws yog ib qho tseem ceeb coenzyme koom nrog ntau yam kev ua haujlwm enzymatic hauv lub cev. PLP ua lub luag haujlwm tseem ceeb hauv kev ua haujlwm ntawm amino acid, kev tsim cov neurotransmitter, thiab kev tsim cov heme, ib feem ntawm hemoglobin.
PLP ua haujlwm ua ib qho coenzyme los ntawm kev khi rau cov enzymes tshwj xeeb thiab pab txhawb rau cov tshuaj lom neeg. Nws ua haujlwm ua ib qho catalyst, pab txhawb kev hloov pauv ntawm ntau yam tshuaj, xws li amino acids, mus rau hauv cov khoom sib txawv. PLP yog qhov tseem ceeb tshwj xeeb hauv kev ua haujlwm ntawm cov amino acids, xws li kev hloov pauv ntawm tryptophan mus rau hauv serotonin, lossis kev tawg ntawm glycine mus rau hauv serine.
Ntxiv rau nws lub luag haujlwm hauv cov amino acid metabolism, PLP kuj tseem koom nrog hauv kev tsim cov neurotransmitters xws li dopamine, norepinephrine, thiab gamma-aminobutyric acid (GABA). Cov neurotransmitters no yog qhov tseem ceeb rau kev ua haujlwm ntawm lub hlwb kom zoo thiab koom nrog kev tswj hwm lub siab, kev paub, thiab kev sib kis ntawm cov cim ntawm cov hlwb hlab ntsha.
Ntxiv mus, PLP yog qhov tsim nyog rau kev tsim cov heme, ib feem ntawm hemoglobin pom muaj nyob rau hauv cov qe ntshav liab. Hemoglobin yog lub luag haujlwm rau kev nqa cov pa oxygen thoob plaws lub cev, ua rau PLP tseem ceeb rau kev tswj cov pa oxygen ib txwm muaj thiab xyuas kom meej tias muaj kev ua haujlwm zoo ntawm ntau yam kabmob thiab cov ntaub so ntswg.
Vim nws tseem ceeb hauv ntau cov txheej txheem biochemical, PLP supplementation qee zaum raug pom zoo rau cov tib neeg uas muaj qee yam mob lossis qhov tsis zoo uas cuam tshuam rau vitamin B6 metabolism. Nws muaj nyob rau hauv daim ntawv ntxiv thiab tuaj yeem raug sau los ntawm cov kws kho mob rau cov kev xav tau tshwj xeeb.
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Reductase, glutathione CAS: 9001-48-3
Glutathione reductase yog ib qho enzyme uas ua lub luag haujlwm tseem ceeb hauv kev tswj qhov sib npaug ntawm cov glutathione txo qis thiab oxidized (GSH/GSSG) hauv cov cell. Glutathione yog ib qho tripeptide uas muaj cov amino acids glycine, cysteine, thiab glutamate. Nws ua haujlwm ua ib qho tseem ceeb ntawm cov cellular antioxidant thiab koom nrog ntau yam txheej txheem cellular, suav nrog kev tshem tawm cov tshuaj lom, kev tsim cov DNA thiab kev kho, thiab kev tsim cov protein.
Glutathione reductase ua rau muaj kev txo qis ntawm oxidized glutathione (GSSG) mus rau nws daim ntawv txo qis (GSH) los ntawm kev siv NADPH (nicotinamide adenine dinucleotide phosphate) ua tus cofactor. Cov tshuaj tiv thaiv no yog qhov tseem ceeb rau kev tswj hwm lub xeev txo qis ntawm glutathione hauv cov hlwb, vim GSSG tuaj yeem sib sau ua ke thaum muaj kev ntxhov siab oxidative.
Los ntawm kev tswj hwm qhov sib piv ntawm GSH rau GSSG, glutathione reductase pab tiv thaiv cov hlwb ntawm kev puas tsuaj oxidative los ntawm cov tshuaj reactive oxygen (ROS) thiab lwm yam tshuaj lom neeg. Nws ua haujlwm ua tus neeg ua si tseem ceeb hauv lub cev tiv thaiv antioxidant ntawm cov hlwb.
Ntxiv mus, glutathione reductase kuj koom nrog kev siv glutathione disulfide (GSSG) uas tsim tawm thaum lub sijhawm ntau yam txheej txheem metabolic, kom ntseeg tau tias muaj glutathione txo qis (GSH) rau nws cov haujlwm ntau ntawm tes.
