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Beta-Amylase CAS: 9000-91-3 Tus nqi tsim khoom
Beta-amylase yog ib qho enzyme uas ua lub luag haujlwm tseem ceeb hauv kev ua cov carbohydrate metabolism, tshwj xeeb tshaj yog hauv kev rhuav tshem lossis hydrolysis ntawm cov hmoov txhuv nplej siab. Nws catalyzes qhov kev txiav ntawm α-1,4-glycosidic bonds hauv cov hmoov txhuv nplej siab, tso tawm maltose thiab ib chav me me hu ua limit dextrin.
Cov enzyme no yog tsim tawm hauv ntau yam kab mob, suav nrog cov nroj tsuag, cov kab mob me me, thiab cov fungi, thiab feem ntau siv rau hauv kev lag luam xws li brewing, ci, thiab biofuel ntau lawm.
Hauv kev ua cawv, beta-amylase ua lub luag haujlwm tseem ceeb hauv kev hloov cov hmoov txhuv nplej siab hauv cov nplej malted mus rau cov suab thaj uas tuaj yeem ferment tau thaum lub sijhawm mashing, pab txhawb rau kev tsim cov cawv los ntawm cov poov xab. Hauv kev ci, nws pab rhuav cov hmoov txhuv nplej siab mus rau hauv cov suab thaj, pab txhawb rau kev ua xim av thiab kev txhim kho saj ntawm cov khoom ci. Hauv kev tsim roj biofuel, beta-amylase yog siv rau hauv kev hydrolysis ntawm cov biomass-based starch kom tau txais cov suab thaj uas tuaj yeem ferment tau siv rau kev tsim ethanol.
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BROMELAIN LOS NTAWM TXIV QAB ZIB CAS: 37189-34-7
Bromelain yog ib qho sib xyaw ntawm cov enzymes uas tau los ntawm cov qia ntawm tsob txiv laum huab xeeb (Ananas comosus). Nws feem ntau yog muaj cov proteases, uas yog cov enzymes uas rhuav cov protein. Bromelain tau siv rau ntau pua xyoo hauv kev kho mob ib txwm ua tshuaj ntsuab rau ntau yam mob.
Vim nws cov khoom ua rau cov protein zom tau, bromelain feem ntau siv los ua ib qho khoom pab zom zaub mov, pab txhim kho kev zom thiab kev nqus cov protein hauv lub cev zom zaub mov. Nws kuj tau raug kawm txog nws cov teebmeem tiv thaiv kev o thiab cov txiaj ntsig zoo rau kev txo qhov o, mob nqaij, thiab mob.
Ntxiv rau nws cov khoom zom zaub mov thiab tiv thaiv kev o, bromelain tau raug tshawb nrhiav txog nws lub peev xwm hauv ntau yam kev siv kho mob, suav nrog kev kho qhov txhab, kev txhawb nqa lub cev tiv thaiv kab mob, thiab kev noj qab haus huv ntawm txoj hlab pa.
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Calpain Inhibitor IV CAS: 133407-82-6
Calpain Inhibitor IV yog ib hom tshuaj uas tsom mus rau thiab tiv thaiv kev ua haujlwm ntawm cov enzyme calpain. Calpain yog ib qho enzyme protease uas nyob ntawm calcium uas ua lub luag haujlwm hauv ntau yam txheej txheem ntawm tes, suav nrog kev xa xov ntawm tes, apoptosis, thiab cytoskeletal remodeling.
Los ntawm kev txwv tsis pub siv calpain, Calpain Inhibitor IV pab tiv thaiv kom tsis txhob muaj kev ua haujlwm ntau dhau thiab tsis tswj tau ntawm cov enzyme no, uas tuaj yeem ua rau lub hlwb puas tsuaj thiab ua haujlwm tsis zoo. Qhov kev txwv no tuaj yeem pab tau rau cov mob uas muaj kev ua haujlwm ntau dhau ntawm calpain, xws li cov kab mob neurodegenerative xws li Alzheimer's thiab Parkinson's, kev raug mob ischemic, lossis cov mob nqaij ntshiv.
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Carboxypeptidase B CAS: 9025-24-5
Carboxypeptidase B yog ib qho enzyme uas ua lub luag haujlwm tseem ceeb hauv kev zom cov protein thiab kev ua haujlwm ntawm cov metabolism. Tshwj xeeb, nws ua rau lub hydrolysis ntawm cov peptide bonds ntawm C-terminal kawg ntawm cov protein, ua rau tshem tawm cov amino acids ib leeg.
Carboxypeptidase B yog qhov tshwj xeeb heev rau cov amino acids yooj yim, xws li lysine thiab arginine, thiab nws muaj txiaj ntsig zoo hauv kev txiav cov residues no. Nws feem ntau pom muaj nyob rau hauv pancreatic secretions thiab koom nrog theem kawg ntawm kev zom cov protein hauv txoj hnyuv me.
Cov enzyme no kuj siv rau hauv ntau yam kev siv hauv chav kuaj mob, suav nrog kev txheeb xyuas cov protein, kev tsim cov peptide, thiab kev tshuaj xyuas cov protein. Lub peev xwm ntawm carboxypeptidase B los txiav cov C-terminal amino acids ntawm cov protein ua rau nws yog ib qho cuab yeej muaj txiaj ntsig zoo rau kev kawm txog cov qauv thiab kev ua haujlwm ntawm cov protein.
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Carboxypeptidase, dipeptidyl, A CAS: 9015-82-1
Carboxypeptidase yog ib qho enzyme uas ua rau lub hydrolysis (kev tawg) ntawm cov peptide bonds ntawm qhov kawg ntawm carboxyl (C-terminal) ntawm peptides thiab cov protein. Nws pab zom thiab ua cov protein los ntawm kev txiav cov amino acids ib leeg ntawm qhov kawg ntawm cov peptide saw. Carboxypeptidases raug muab faib ua ob hom: exopeptidases, uas tshem cov amino acids ib zaug ntawm qhov kawg ntawm C-terminal, thiab endopeptidases, uas txiav cov peptide bonds hauv cov peptide saw. Cov enzymes no ua lub luag haujlwm tseem ceeb hauv ntau yam txheej txheem biological, suav nrog protein metabolism, kev tswj cov tshuaj hormones, thiab kev tswj cov enzymatic activity.
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Coenzyme A sodium ntsev hydrate CAS: 55672-92-9
Coenzyme A sodium ntsev hydrate yog ib hom Coenzyme A (CoA) uas yaj tau hauv dej, uas yog ib qho coenzyme tseem ceeb uas koom nrog ntau txoj kev zom zaub mov. Nws ua lub luag haujlwm tseem ceeb hauv kev rhuav tshem cov rog, carbohydrates, thiab cov protein, nrog rau kev tsim cov molecules tseem ceeb xws li fatty acids thiab cholesterol. Coenzyme A sodium ntsev hydrate feem ntau siv rau hauv kev tshawb fawb biochemical thiab tshuaj ua ib qho khoom noj ntxiv los kawm txog kev zom zaub mov ntawm tes thiab cov txheej txheem cuam tshuam.
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5-Nitro-1,10-phenanthroline CAS: 4199-88-6
5-Nitro-1,10-phenanthroline yog ib qho tshuaj lom neeg uas muaj cov mis molecular C12H6N4O2. Nws yog ib feem ntawm tsev neeg ntawm phenanthroline derivatives thiab muaj ib pawg nitro (-NO2) txuas rau 5-txoj haujlwm ntawm lub nplhaib phenanthroline.
Cov tshuaj no paub txog nws lub peev xwm los tsim cov khoom sib xyaw ruaj khov nrog cov hlau ions, tshwj xeeb tshaj yog cov hlau hloov pauv. Pawg nitro txhim kho nws cov khoom sib xyaw thiab ua rau nws muaj txiaj ntsig zoo hauv ntau yam kev siv xws li kev tshuaj xyuas tshuaj, catalysis, thiab kev sib koom tes tshuaj.
5-Nitro-1,10-phenanthroline tau siv los ua ib qho chelator, uas txhais tau tias nws tsim cov kev sib txuas ruaj khov nrog cov hlau ions los ntawm kev pub cov khub electrons ib leeg. Qhov no tso cai rau kev tswj hwm thiab kev tswj hwm qhov chaw sib koom tes ntawm cov hlau-ion.
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Acetyl coenzyme A sodium ntsev CAS: 102029-73-2
Acetyl coenzyme A (acetyl-CoA) sodium ntsev yog ib qho khoom siv hluavtaws ntawm acetyl-CoA. Nws feem ntau yog siv rau hauv kev tshawb fawb hauv chav kuaj thiab kev tshawb fawb biochemical.
Daim ntawv thov tseem ceeb ntawm acetyl-CoA sodium ntsev yog nyob rau hauv kev tshawb fawb txog kev ua haujlwm ntawm lub cev, tshwj xeeb tshaj yog hauv kev tshawb nrhiav lub luag haujlwm ntawm acetyl-CoA hauv ntau txoj kev ua haujlwm ntawm lub cev. Acetyl-CoA ua haujlwm ua tus ua ntej rau kev tsim cov roj fatty acids, cholesterol, thiab ketone lub cev, nrog rau ua lub luag haujlwm tseem ceeb hauv kev tsim hluav taws xob los ntawm lub voj voog citric acid (tseem hu ua Krebs voj voog).
Tsis tas li ntawd xwb, acetyl-CoA koom nrog rau hauv kev ua acetylation ntawm cov protein, DNA, thiab histones, uas tuaj yeem cuam tshuam rau kev qhia tawm gene thiab chromatin remodeling. Yog li ntawd, acetyl-CoA sodium ntsev tuaj yeem siv rau hauv kev tshawb fawb tsom mus rau cov kev hloov pauv epigenetic no thiab lawv cov kev cuam tshuam rau kev ua haujlwm ntawm lub hlwb.
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Puromycin dihydrochloride CAS: 58-58-2 Tus nqi tsim khoom
Puromycin dihydrochloride yog ib yam tshuaj tua kab mob muaj zog uas feem ntau siv rau hauv kev tshawb fawb txog molecular biology thiab cell biology. Nws tiv thaiv kev tsim cov protein los ntawm kev ua rau kev tsim cov protein tsis ua haujlwm sai sai thaum lub sijhawm txhais lus. Puromycin muaj txiaj ntsig zoo rau ob qho tib si prokaryotic thiab eukaryotic hlwb thiab nws yog qhov tshwj xeeb tshaj yog rau kev xaiv thiab kev rho tawm cov hlwb uas tau hloov kho lossis hloov pauv nrog cov noob caj noob ces tiv thaiv puromycin. Nws feem ntau yog siv rau hauv chaw kuaj mob los kawm txog kev qhia txog noob caj noob ces, kev tsim cov protein, thiab los tsim cov kab mob cell ruaj khov nrog kev hloov kho noob caj noob ces tshwj xeeb.
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Acetylcholinesterase CAS: 9000-81-1
Cov tshuaj Anticholinesterases yog ib hom tshuaj lossis tshuaj lom neeg uas txwv tsis pub cov enzyme acetylcholinesterase ua haujlwm. Acetylcholinesterase yog lub luag haujlwm rau kev rhuav tshem cov neurotransmitter acetylcholine hauv lub cev. Los ntawm kev txwv cov enzyme no, anticholinesterases ua rau cov acetylcholine ntau ntxiv, ua rau muaj kev ua haujlwm cholinergic ntau ntxiv hauv cov hlab ntsha hauv nruab nrab thiab cov hlab ntsha peripheral.
Kev siv cov tshuaj anticholinesterases tseem ceeb rau kev kho mob yog siv rau kev kho cov kab mob neurological xws li Alzheimer's tus kab mob thiab myasthenia gravis. Hauv Alzheimer's tus kab mob, cov tshuaj no lub hom phiaj yog txhawb kev xa cov cholinergic neurotransmission thiab tej zaum yuav qeeb qeeb kev poob qis ntawm kev paub. Hauv myasthenia gravis, anticholinesterases pab txhim kho kev xa cov neuromuscular thiab cov leeg nqaij muaj zog.
Lwm yam kev siv tshuaj anticholinesterases suav nrog kev kuaj mob thiab kev kho mob ntawm kev lom tshuaj anticholinergic, tshwj xeeb tshaj yog los ntawm qee cov tshuaj tua kab lossis cov tshuaj ua rau cov hlab ntsha. Cov tshuaj no tuaj yeem ua rau muaj kev txhawb nqa ntau dhau ntawm cov muscarinic thiab nicotinic receptors, ua rau muaj cov tsos mob xws li cov leeg tsis muaj zog, tshee hnyo, thiab ua pa nyuaj. Anticholinesterases tuaj yeem thim rov qab cov teebmeem no los ntawm kev nce qib acetylcholine thiab kev sib tw nrog cov tshuaj lom.
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Rapamycin los ntawm Streptomyces hygroscopicus CAS: 53123-88-9
Rapamycin yog ib qho tshuaj uas muaj nyob hauv ntuj tsim los ntawm cov kab mob Streptomyces hygroscopicus. Nws muaj ntau yam kev ua haujlwm ntawm lub cev thiab feem ntau paub txog nws cov khoom tiv thaiv kab mob thiab tiv thaiv kab mob qog noj ntshav.
Chiv thawj pom tias yog ib yam tshuaj tua kab mob fungal, rapamycin tau pom tias muaj cov khoom tiv thaiv kab mob zoo, ua rau nws muaj txiaj ntsig zoo rau kev hloov pauv lub cev kom tiv thaiv kev tsis lees txais. Nws ua qhov no los ntawm kev txwv tsis pub ua haujlwm thiab kev loj hlob ntawm T-cell, ib qho tseem ceeb ntawm kev tiv thaiv kab mob.
Tsis tas li ntawd xwb, rapamycin tau pom tias muaj txiaj ntsig zoo hauv kev kho mob ntau yam mob qog noj ntshav. Nws ua haujlwm los ntawm kev txwv tsis pub muaj cov protein hu ua mTOR (mammalian target of rapamycin), uas ua lub luag haujlwm tseem ceeb hauv kev loj hlob thiab kev faib ntawm cov cell. Los ntawm kev thaiv mTOR, rapamycin pab tswj kev loj hlob ntawm cov cell qog noj ntshav uas tsis raug tswj.
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Acylase los ntawm Aspergillus genus CAS: 9012-37-7
Acylase yog ib qho enzyme tsim los ntawm ntau hom tsiaj los ntawm Aspergillus genus, suav nrog Aspergillus oryzae thiab Aspergillus niger. Cov enzyme no yog ib feem ntawm tsev neeg ntawm hydrolases thiab koom nrog hauv hydrolysis ntawm acyl compounds.
Cov acylases ua lub luag haujlwm tseem ceeb hauv ntau yam txheej txheem biochemical, tshwj xeeb tshaj yog hauv kev ua cov organic compounds. Lawv ua rau muaj kev sib cais ntawm cov pab pawg acyl los ntawm cov substrate, feem ntau siv dej ua cov tshuaj sib koom ua ke. Cov tshuaj tiv thaiv enzymatic no hu ua acyl hydrolysis.
Cov acylases los ntawm Aspergillus genus tau raug kawm thiab siv dav hauv kev siv biotechnological. Lawv tau pom tias muaj peev xwm loj hauv kev tsim ntau yam khoom muaj nqis xws li amino acids, tshuaj tua kab mob, thiab lwm yam tshuaj intermediates.
