Gabapentin CAS: 60142-96-3 Chaw tsim tshuaj paus

Gabapentin yog ib qho Amino acid structurally ntsig txog γ-Aminobutyric Acid (GABA), tsim los hla cov hlab ntsha hlwb.Siv raws li ib tug anticonvulsant.Nws kuj tau raug sau tseg rau ntau tus neeg mob sclerosis los tswj dysesthesias thiab tej zaum yuav muaj txiaj ntsig hauv kev txo cov mob neuropathic los ntawm kev mob qog noj ntshav thiab kab mob HIV.Nws tsis khi rau GABA receptors, tsis cuam tshuam rau neural uptake ntawm GABA, thiab tsis inhibit GABA-metabolizing enzyme, GABA transaminase.Tsis zoo li GABA, uas tsis dhau los ntawm cov ntshav-hlwb teeb meem, gabapentin nkag mus rau hauv lub hauv nruab nrab lub paj hlwb thiab khi rau α2δ-hom voltage-gated calcium channels.Cov txheej txheem rau analgesic thiab anticonvulsant teebmeem ntawm gabapentin tsis paub.