Gabapentin CAS: 60142-96-3 Chaw Tsim Khoom

Gabapentin yog ib qho amino acid uas muaj feem cuam tshuam nrog γ-Aminobutyric Acid (GABA), uas tsim los hla cov ntshav hauv lub hlwb. Siv ua tshuaj anticonvulsant. Nws kuj tseem raug sau rau cov neeg mob ntau yam sclerosis kom tswj tau dysesthesia thiab tej zaum yuav pab tau rau kev txo qhov mob neuropathic los ntawm mob qog noj ntshav thiab HIV. Nws tsis khi rau GABA receptors, tsis cuam tshuam rau neural uptake ntawm GABA, thiab tsis inhibit GABA-metabolizing enzyme, GABA transaminase. Tsis zoo li GABA, uas tsis hla cov ntshav-lub hlwb barrier, gabapentin nkag mus rau hauv lub paj hlwb thiab khi rau α2δ-hom voltage-gated calcium channels. Lub mechanism rau analgesic thiab anticonvulsant cov teebmeem ntawm gabapentin tsis paub.