Orlistat CAS: 96829-58-2 Chaw Tsim Khoom

Orlistat yog ib qho semi-synthetic derivative ntawm lipstatin, ib qho metabolite cais los ntawm Streptomyces toxytricini. Tetrahydrolipstatin ua haujlwm ua ib qho muaj zog, irreversible inhibitor ntawm pancreatic lipase. Hauv vivo, nws thaiv kev nqus ntawm triglycerides thaum tso cai rau fatty acid nqus. Tetrahydrolipstatin yog dav siv rau kev kho mob rog dhau. Orlistat muaj cov nyhuv tswj qhov hnyav mus sij hawm ntev uas txo thiab tswj qhov hnyav thiab tiv thaiv kev rov qab los. Kev siv Orlistat tuaj yeem txo qhov tshwm sim ntawm cov yam ntxwv thiab kab mob ntsig txog qhov hnyav, suav nrog hypercholesterolemia, hom-2 ntshav qab zib, impaired glucose tolerance, hyperinsulinemia, thiab ntshav siab, thiab nws tuaj yeem txo cov rog hauv cov kabmob.