1,7-Dimethylindolin-2-ib CAS: 67358-21-8

1,7-Dimethylindolin-2-ib ua lub luag haujlwm tseem ceeb ua ib qho nruab nrab hauv kev tsim cov tshuaj sib xyaw ua ke, cov tshuaj bioactive nrog cov kev siv tshuaj. Nws txoj kev koom ua ke rau hauv cov qauv molecular ua rau cov kws tshawb fawb tshawb nrhiav cov tshuaj tshiab uas tsom mus rau thaj chaw kho mob xws li cov kab mob hauv lub paj hlwb, cov tshuaj tua kab mob, lossis cov ntaub ntawv siv tshuaj. Qhov muaj nyob ntawm indolinone core qhia txog kev ua haujlwm tshwj xeeb thiab cov khoom pharmacophoric, ua rau nws muaj txiaj ntsig zoo rau kev tshawb fawb txog tshuaj. Hauv kev siv zog nrhiav tshuaj, cov tshuaj no yuav ua lub hauv paus rau kev tsim cov tshuaj muaj peev xwm, siv nws cov yam ntxwv ntawm cov qauv los hloov kho cov haujlwm biological thiab cov khoom pharmacokinetic. Tsis tas li ntawd, cov qauv tshwj xeeb ntawm lub molecule muab cov sijhawm rau kev sib txawv, uas ua rau muaj kev txhim kho cov tshuaj tshiab nrog cov khoom biological zoo dua thiab cov qauv pharmacokinetic zoo dua. Ntxiv mus, hauv kev kawm thiab kev lag luam, cov kws tshawb fawb tuaj yeem siv lub tsev thaiv no los npaj cov tsev qiv ntawv ntawm ntau yam derivatives rau kev tshawb fawb txog kev sib raug zoo ntawm cov qauv thiab kev ua haujlwm, pab txhawb kev txheeb xyuas cov tshuaj txhuas nrog cov teebmeem biological xav tau. Nws lub luag haujlwm hauv kev tsim tshuaj lom neeg txuas ntxiv mus rau kev tsim cov tshuaj intermediates thiab kev txhim kho cov txheej txheem tsim tshiab, qhia txog nws cov txiaj ntsig dav dav thoob plaws kev tshawb fawb. Zuag qhia tag nrho, 1,7-Dimethylindolin-2-ib ua lub luag haujlwm tseem ceeb hauv kev nrhiav kev tshawb pom tshuaj tshiab thiab kev tshawb fawb txog tshuaj lom neeg, muab lub platform rau kev tsim cov tshuaj lom neeg ntau yam thiab cov tshuaj nruab nrab.