(R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate CAS: 955406-14-1

(R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate ua lub luag haujlwm tseem ceeb ua ib qho nruab nrab hauv kev tsim cov tshuaj sib xyaw ua ke, cov tshuaj bioactive nrog cov ntawv thov tshuaj. Nws qhov xwm txheej chiral thiab cov yam ntxwv tshwj xeeb tso nws ua ib qho tseem ceeb rau kev tsim cov tshuaj enantiopure, uas yog qhov tseem ceeb hauv kev tsim tshuaj. Los ntawm kev koom ua ke cov khoom siv no rau hauv cov qauv molecular, cov kws tshawb fawb tuaj yeem tshawb nrhiav cov neeg sib tw tshuaj tshiab uas tsom mus rau thaj chaw kho mob xws li cov kab mob hauv lub paj hlwb hauv nruab nrab, cov kab mob sib kis, lossis oncology. Hauv kev kho mob tshuaj, cov tshuaj no tuaj yeem ua lub hauv paus rau kev tsim cov neeg sib tw tshuaj, siv nws cov stereochemistry los hloov kho cov haujlwm biological thiab cov khoom pharmacokinetic. Pawg tert-butyl muab kev cuam tshuam steric thiab cuam tshuam rau cov tshuaj sib cuam tshuam nrog cov hom phiaj biological, pab txhawb rau kev tshawb nrhiav cov kev kho mob tshiab. Ntxiv mus, hauv kev kawm thiab kev lag luam, cov kws tshawb fawb tuaj yeem siv cov khoom siv no los npaj cov tsev qiv ntawv ntawm ntau yam derivatives rau kev tshawb fawb txog kev sib raug zoo ntawm cov qauv thiab kev ua haujlwm, pab txhawb kev txheeb xyuas cov tshuaj txhuas nrog cov teebmeem biological xav tau. Nws lub luag haujlwm hauv kev tsim tshuaj lom neeg txuas ntxiv mus rau kev tsim cov tshuaj intermediates thiab kev tsim cov txheej txheem tsim tshiab, qhia txog nws cov txiaj ntsig dav dav thoob plaws kev tshawb fawb. Zuag qhia tag nrho, (R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate ua lub luag haujlwm tseem ceeb hauv kev nrhiav kev tshawb pom tshuaj tshiab thiab kev sib xyaw ua ke tsis sib xws, muab lub platform rau kev tsim cov tshuaj lom neeg thiab cov tshuaj intermediates.