(2S,4S)-1-Boc-4-Aminopyrrolidine-2-carboxylic acid CAS: 132622-66-3

(2S,4S)-1-Boc-4-aminopyrrolidine-2-carboxylic acid ua haujlwm ua ib qho tseem ceeb hauv kev tsim cov tshuaj sib xyaw ua ke, cov tshuaj bioactive nrog cov ntawv thov tshuaj. Nws qhov xwm txheej chiral thiab cov yam ntxwv tshwj xeeb tso nws ua ib qho tseem ceeb rau kev tsim cov tshuaj enantiopure, uas yog qhov tseem ceeb hauv kev tsim tshuaj. Los ntawm kev koom ua ke cov khoom siv no rau hauv cov qauv molecular, cov kws tshawb fawb tuaj yeem tshawb nrhiav cov neeg sib tw tshuaj tshiab uas tsom mus rau thaj chaw kho mob xws li tshuaj tua kab mob, tshuaj antineoplastics, lossis cov kab mob hauv lub paj hlwb. Hauv kev kho mob chemistry, cov tshuaj no tuaj yeem ua lub hauv paus rau kev tsim cov neeg sib tw tshuaj, siv nws cov stereochemistry los hloov kho cov haujlwm biological thiab cov khoom pharmacokinetic. Kev tiv thaiv Boc ntawm cov amino pawg muab kev tswj hwm kev ua haujlwm thiab kev xaiv thaum lub sijhawm hloov pauv synthetic tom qab, ua rau kev tsim cov qauv tshuaj sib txawv. Ntxiv mus, hauv kev kawm thiab kev lag luam, cov kws tshawb fawb tuaj yeem siv cov khoom siv no los npaj cov tsev qiv ntawv ntawm ntau yam derivatives rau kev tshawb fawb txog kev sib raug zoo ntawm cov qauv thiab kev ua haujlwm, pab txhawb kev txheeb xyuas cov tshuaj txhuas nrog cov teebmeem biological xav tau. Nws lub luag haujlwm hauv kev tsim tshuaj lom neeg txuas ntxiv mus rau kev tsim cov tshuaj intermediates thiab kev txhim kho cov txheej txheem tshiab, qhia txog nws cov txiaj ntsig dav dav thoob plaws kev tshawb fawb. Zuag qhia tag nrho, (2S,4S)-1-Boc-4-aminopyrrolidine-2-carboxylic acid ua lub luag haujlwm tseem ceeb hauv kev nrhiav kev tshawb pom tshuaj tshiab thiab kev sib xyaw ua ke tsis sib xws, muab lub platform rau kev txhim kho ntau yam tshuaj lom neeg thiab cov tshuaj nruab nrab.