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Hydrocortisone Base CAS: 50-23-7 Chaw Tsim Khoom Siv
Hydrocortisone, 11β, 17,21-trihydroxypregn-4-ene-3,20-dione, yog thawj GCin tib neeg. Txawm hais tias muaj ntau cov GCs tsim los, hydrocortisone, nws cov esters, thiab nws cov ntsev tseem yog lub hauv paus ntawm kev kho mob adrenocortical steroid niaj hnub thiab tus qauv rau kev sib piv ntawm txhua lwm yam GCs thiab MCs. Nws yog siv rau txhua qhov kev qhia tau hais ua ntej.
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Orlistat CAS: 96829-58-2 Chaw Tsim Khoom
Orlistat yog ib qho tshuaj uas ua rau cov lipase hauv plab zom mov tsis ua haujlwm. Orlistat tau tsim tawm hauv UK ua Xenical rau kev kho mob rog ntev, zoo dua yog tias noj nrog kev noj zaub mov uas tsis muaj calorie ntau. Orlistat yog tetrahydro-derivative ntawm cov tshuaj hypolipaemic lipstatin ntuj (los ntawm Streptomyces toxyfncini) thiab tuaj yeem tau txais los ntawm hydrogenation ntawm lipstatine lossis los ntawm ntau txoj kev sib txawv uas muaj ntau kauj ruam los ntawm (S) - rnalic acid.
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L-Homoarginine Monohydrochloride CAS: 1483-01-8 Chaw Tsim Khoom Siv
L-Homoarginine yog ib qho tshuaj uas tsis sib tw thiab tshwj xeeb rau cov kab mob uas ua rau alkaline phosphatases tsis sib xws. Cov amino acid no tsis tseem ceeb inhibits tib neeg cov pob txha thiab daim siab alkaline phosphatases tab sis tsis muaj kev cuam tshuam rau placental lossis plab hnyuv isoenzymes. Kev kho mob ua ntej nrog L-homoarginine qeeb hauv vivo kev loj hlob ntawm qog hauv tus qauv murine C3H / He osteosarcoma. Nws kuj tseem inhibits kev noj zaub mov muaj protein ntau ua rau pancreatic loj hlob thiab enzyme secretion hauv cov nas uas tau hloov cov kua txiv bile-pancreatic, ib qho qauv rau kev ua kom pancreatic enzyme secretion nrog hypercholecystokininemia..
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Escitalopram Oxalate CAS: 219861-08-2
Escitalopram oxalate yog ib qho metabolite S-isomer ntawm citalopram thiab yog qhov tseem ceeb ntawm nws cov haujlwm pharmacological. Nws lub npe tshuaj yog (S) -1- [3- (dimethylamino) propyl] -1- (Chemicalbook4-fluorophenyl) -1,3-dihydroisobenzofuran 5-acetonitrile oxalate, Nws yog ib qho kev xaiv serotonin reuptake inhibitor, Nws muaj cov txiaj ntsig zoo rau kev kho mob ob qho tib si endogenous thiab tsis endogenous kev nyuaj siab.
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Txo Glutathione CAS: 70-18-8 Chaw Tsim Khoom
Glutathione (GSH) yog ib qho tripeptide (γ-glutamylcysteinylglycine) uas muaj ntau nyob rau hauv cov nroj tsuag thiab tsiaj txhu. GSH ua haujlwm ua ib qho nucleophilic co-substrate rau glutathione transferases hauv kev tshem tawm cov tshuaj xenobiotics thiab yog ib qho tseem ceeb electron donor rau glutathione peroxidases hauv kev txo cov hydroperoxides. GSH kuj tseem koom nrog kev thauj amino acid thiab kev tswj hwm cov protein sulfhydryl txo qis. Qhov concentration ntawm GSH yog los ntawm ob peb micromolar hauv plasma mus rau ntau millimolar hauv cov ntaub so ntswg xws li siab.
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Cysteine CAS: 52-90-4 Chaw Tsim Khoom Siv
L-Cysteine yog ib qho ntawm 20 cov amino acids ntuj thiab, ntxiv rau methionine, tsuas yog ib qho uas muaj sulfur. Nws yog ib qho thiol-muaj cov amino acid tsis tseem ceeb uas tau oxidized los ua Cystine. Nws yog ib qho tsis tseem ceeb sulfur-muaj amino acid hauv tib neeg, cuam tshuam nrog cystine, Cysteine yog qhov tseem ceeb rau kev tsim cov protein, kev tshem tawm cov tshuaj lom, thiab ntau yam kev ua haujlwm metabolic. Pom muaj nyob rau hauv beta-keratin, cov protein tseem ceeb hauv cov rau tes, tawv nqaij, thiab plaub hau, Cysteine yog qhov tseem ceeb hauv kev tsim collagen, nrog rau daim tawv nqaij elasticity thiab kev ntxhib los mos.
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Coenzyme A kua qaub dawb CAS: 85-61-0
Coenzyme A kua qaub dawbyog ib qho tseem ceeb cofactor ua haujlwm ua tus neeg nqa khoom acyl thiab carbonyl-activating pawg rau lub voj voog citric acid thiab fatty acid metabolism. Kwv yees li 4% ntawm cov cellular enzymes siv CoA ua lub substrate. Nws yog synthesized los ntawm pantothenic acid hauv 5-kauj ruam txheej txheem uas xav tau ATP. Cov kauj ruam pantothenate kinase ntawm CoA biosynthetic pathway tau txheeb xyuas tias yog lub hom phiaj rau kev tsim cov tshuaj tua kab mob.
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Idebenone CAS: 58186-27-9 Chaw Tsim Khoom Siv
Idebenone yog ib qho organic compound uas yog los ntawm tsev neeg quinone, zoo ib yam li coenzyme Q-10. Nws yog ib hom tshuaj uas Takeda Pharmaceutical Company tsim los kho tus kab mob Alzheimer thiab qee qhov teeb meem kev paub. Txawm li cas los xij, cov no tsis tau muaj kev vam meej ntau nrog rau qhov cim no. Tam sim no nws kuj siv rau kev kho mob Friedreich's ataxia nrog rau qhov cuam tshuam zoo rau lub plawv hypertrophy thiab kev ua haujlwm ntawm lub paj hlwb.
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Tetracaine Hydrochloride CAS: 136-47-0 Chaw Tsim Khoom Siv
Tetracaine hydrochloride yog ib qho benzoate ester. Nws yog ib qho tshuaj loog hauv zos uas muaj zog ntawm hom ester siv rau kev siv tshuaj loog saum npoo thiab tus txha caj qaum. Tetracaine hydrochloride yog ib qho tshuaj loog hauv zos thiab yog ib qho ester derivative ntawm p-amino benzoic acid. Nws ua haujlwm los ntawm kev cuam tshuam kev nkag mus ntawm sodium ions rau hauv cov hlwb paj hlwb thiab yog ib qho ntawm cov tshuaj loog siv feem ntau.
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Leucine CAS: 61-90-5 Chaw Tsim Khoom
Leucine yog ib qho ntawm yim cov amino acids tseem ceeb, thiab koom nrog cov aliphatic amino acids hauv nees nkaum hom protein. L-leucine thiab L-isoleucine thiab L-valine hu ua peb ceg amino acids. L-leucineLeucine thiab D-leucine yog enantiomers. Nws yog ib qho dawb ci ntsa iab hexahedral siv lead ua los yog dawb crystalline hmoov ntawm chav tsev kub, Tsis muaj ntxhiab, me ntsis iab. Nyob rau hauv lub xub ntiag ntawm hydrocarbons, nws ruaj khov nyob rau hauv aqueous mineral acid. Ib gram yog yaj rau hauv 40ml dej thiab txog 100ml acetic acid. Me ntsis soluble nyob rau hauv ethanol lossis ether, yaj rau hauv formic acid, dilute hydrochloric acid, ib qho kev daws teeb meem ntawm alkali hydroxides thiab ib qho kev daws teeb meem ntawm carbonates.
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Guanidinopropionic Acid CAS: 353-09-3 Chaw Tsim Khoom
Guanidinopropionic acid yog ib qho siv lead dawb uas yaj hauv dej thiab yog ib qho creatine analog. Guanidinopropionic acid yog ib hom amino acid derivatives. Nws yog ib qho tseem ceeb hauv cov tshuaj raw khoom thiab nruab nrab. Nws muaj nyob rau hauv cov ntshav, lub hlwb, siab, raum thiab zis ntawm cov tsiaj txhu.
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Olmesartan CAS: 144689-24-7 Chaw Tsim Khoom
Olmesartan medoxomil, phenyl]phenyl]methyl]imidazole-4-carboxylate (Benicar, Olmetec) siv lub kaw lus tetrazolering ua nws lub kaw lus acidic, uas koom nrog hauv kev khi receptor. Thaum muab rau tus neeg mob, cov tshuaj sai thiab tag nrho bioactivated los ntawm ester hydrolysis ntawm medoxomil thaum lub sijhawm nqus los ntawm txoj hnyuv plab. Olmesartan yog biphenylyltetrazole. Nws muaj lub luag haujlwm ua tus neeg sawv cev tiv thaiv ntshav siab thiab angiotensin receptor antagonist.
