methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate CAS: 362703-30-8

Methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate ua lub luag haujlwm tseem ceeb ua ib qho nruab nrab uas muaj ntau yam hauv kev tsim cov tshuaj sib xyaw ua ke, cov tshuaj bioactive nrog cov ntawv thov tshuaj. Nws txoj kev koom ua ke rau hauv cov qauv molecular tso cai rau cov kws tshawb fawb tshawb nrhiav cov tshuaj tshiab uas tsom mus rau thaj chaw kho mob xws li cov kab mob plawv, cov kab mob hauv lub paj hlwb, lossis cov neeg sawv cev tiv thaiv kab mob. Qhov muaj tetrahydropyran core thiab cyano functionality qhia txog cov tshuaj reactivity thiab pharmacophoric tshwj xeeb, ua rau nws muaj txiaj ntsig zoo rau kev tshawb fawb txog tshuaj. Hauv kev siv zog nrhiav tshuaj, cov tshuaj no tuaj yeem ua lub hauv paus pib rau kev tsim cov tshuaj muaj peev xwm, siv nws cov yam ntxwv ntawm cov qauv los hloov kho cov haujlwm biological thiab cov khoom pharmacokinetic. Tsis tas li ntawd, pawg cyano tuaj yeem ua haujlwm ua tus kov ntau yam rau kev sib txuas ntxiv, tso cai rau kev tshawb nrhiav cov qauv-kev ua ub no thiab kev txhim kho cov tshuaj tshiab. Tsis tas li ntawd, hauv kev kawm thiab kev lag luam, cov kws tshawb fawb tuaj yeem siv lub tsev thaiv no los npaj cov tsev qiv ntawv ntawm ntau yam derivatives rau kev tshawb fawb txog kev sib raug zoo ntawm cov qauv-kev ua ub no, pab txhawb kev txheeb xyuas cov tshuaj txhuas nrog cov teebmeem biological xav tau. Nws lub luag haujlwm hauv kev tsim tshuaj lom neeg nthuav dav mus rau kev tsim cov tshuaj intermediates thiab kev tsim cov txheej txheem tsim tshiab, qhia txog nws cov txiaj ntsig dav dav thoob plaws kev tshawb fawb. Zuag qhia tag nrho, Methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate ua lub luag haujlwm tseem ceeb hauv kev nrhiav kev tshawb pom tshuaj tshiab thiab kev tshawb fawb txog tshuaj lom neeg, muab lub platform rau kev tsim cov tshuaj lom neeg ntau yam thiab cov tshuaj intermediates.