Letrozole CAS: 112809-51-5 Chaw tsim tshuaj paus

Letrozole yog ib feem ntawm lub cim tshiab ntawm kev xaiv aromatase inhibitors thiab yog ib qho khoom siv hluavtaws benzotriazole derivative.Letrozole inhibits aromatase kom txo qis cov tshuaj estrogen, yog li tiv thaiv cov tshuaj estrogen los ntawm stimulating qog loj hlob.Nws cov haujlwm hauv vivo yog 150-250 lub sijhawm muaj zog dua li ntawm thawj tiam aromatase inhibitor Amarante.Raws li nws muaj kev xaiv heev, nws yuav tsis cuam tshuam rau glucocorticoid, mineralocorticoid thiab cov thyroid ua haujlwm;Txawm tias muaj ntau npaum li cas, nws yuav tsis muaj qhov cuam tshuam rau adrenal corticosteroid secretion, muab nws qhov kev kho mob siab.

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Letrazole tuaj yeem ua ke hauv ob kauj ruam los ntawm 4- bromomethyl-benzonitrile nrog 1,2,4-triazole thiab yog ib tiam thib peb ntawm aromatase inhibitor.Nws yog ib qho tshwj xeeb inhibitor ntawm P450arom uas tiv thaiv kev hloov pauv ntawm androstenedione rau estrone.Qhov txo qis ntawm plasma estrogen yog tam sim ntawd thiab kav ntev.Qhov no ua tiav nrog tsis muaj kev cuam tshuam ntawm lwm yam steroid biosynthesis ua rau nws qhov kev xaiv ntau tshaj plaws aromatase inhibitor kuaj.Letrazole muaj cov tshuaj tiv thaiv kab mob zoo tshaj plaws, tiv taus zoo thiab tsis muaj tshuaj lom.Nws yog 10,000 lub sij hawm ntau zog tshaj aminoglutethimide, nyob rau hauv vivo, thawj zoo tsim aromatase inhibitor.

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Cov ntaub ntawv ntxiv:

Kev sib xyaw	C17H11N5
Assay	99%
Qhov tshwm sim	Dawb hmoov
CAS Nr.	112809-51-5
Ntim	25 KG
Txee lub neej	2 xyoo
Cia	Khaws rau hauv qhov chaw txias thiab qhuav
Daim ntawv pov thawj	ISO.