Fmoc-Asp(OBut)-OSu CAS:78553-23-8

Fmoc-Asp(OBut)-OSu ua haujlwm ua ib qho cuab yeej siv tau ntau yam hauv kev tsim cov peptide, tshwj xeeb tshaj yog hauv kev tsim cov peptides uas muaj aspartic acid nrog kev ua kom raug. Pawg tiv thaiv Fmoc tiv thaiv pawg amino, ua kom muaj kev xaiv thaum lub sijhawm sib txuas peptide, thaum pawg O-butyl ntxiv ib txheej ntxiv ntawm kev tiv thaiv rau pawg carboxyl. Lub luag haujlwm OSu ester ua rau muaj kev sib txuas amide zoo thiab xaiv tau thaum lub sijhawm sib txuas peptide. Cov kws tshawb fawb siv Fmoc-Asp(OBut)-OSu ntau hauv kev tsim cov peptides rau ntau yam kev siv, suav nrog kev tsim tshuaj, cov khoom siv biomaterials, thiab kev tsim cov peptides bioactive nrog cov yam ntxwv tshwj xeeb. Nws qhov sib xws nrog cov txheej txheem tsim peptide txheem, hauv ob qho tib si theem khov thiab theem daws teeb meem, txhim kho nws qhov kev ua tau zoo hauv ntau yam kev tshawb fawb. Kev tshem tawm tswj hwm ntawm cov pab pawg tiv thaiv tso cai rau kev koom ua ke ntawm aspartic acid rau hauv cov kab ke peptide, nthuav dav ntau yam ntawm cov peptides synthesizable. Ntxiv mus, Fmoc-Asp(OBut)-OSu pom tias muaj txiaj ntsig zoo hauv kev tsim cov peptides rau kev tshawb fawb proteomics thiab kawm txog cov txheej txheem cellular. Kev siv O-butyl tiv thaiv pawg ua rau muaj kev tswj hwm qhov tseeb ntawm aspartic acid reactivity, thiab OSu ester pawg pab txhawb kev sib txuas lus thiab kev sau npe ntawm peptides. Hauv kev xaus, Fmoc-Asp(OBut)-OSu sawv cev rau lub cuab yeej tseem ceeb thiab tsis tseem ceeb hauv peptide chemistry, txhawb nqa cov kws tshawb fawb los tshawb nrhiav thiab hloov kho aspartic acid reactivity rau ntau yam kev siv tshawb fawb, tshwj xeeb tshaj yog tsom mus rau peptides nrog kev ua haujlwm zoo dua los ntawm OSu ester pawg.