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Lasmiditant CAS: 439239-90-4
Lasmiditan, muag hauv lub npe lag luam Reyvow, yog ib hom tshuaj tshiab uas tsim los pab txo qhov mob taub hau loj heev rau cov neeg laus. Nws yog ib hom tshuaj serotonin receptor agonists, tshwj xeeb tshaj yog rau 5-HT1F receptor subtype. Lub tshuab ua haujlwm no ua rau Lasmiditan txawv ntawm kev kho mob taub hau ib txwm muaj, vim nws tsis ua rau cov hlab ntsha nqaim, ua rau nws haum rau cov neeg mob uas muaj feem yuav mob plawv.
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N-Methylcarbonyl-2-chloroacetamidrazone CAS: 155742-64-6
N-Methylcarbonyl-2-chloroacetamidrazone yog ib hom tshuaj uas paub txog nws cov kev siv tau ntau yam hauv kev tsim cov organic thiab kev sib koom tes chemistry. Nws cov kev sib xyaw ua ke suav nrog kev sib xyaw ntawm N-methylcarbamoyl chloride nrog 2-chloroacetohydrazide, ua rau muaj cov tshuaj uas muaj cov yam ntxwv sib txawv thiab kev ua haujlwm. Cov tshuaj no yog tus cwj pwm los ntawm nws lub peev xwm los tsim cov complexes nrog ntau yam hlau ions, ua rau nws muaj txiaj ntsig zoo hauv kev kawm txog kev sib koom tes chemistry. Tsis tas li ntawd, nws cov pab pawg carbonyl thiab amidrazone pab txhawb rau nws cov tshuaj tiv thaiv thiab cov haujlwm pharmacological, uas yog cov cheeb tsam ntawm kev tshawb fawb txuas ntxiv mus.
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Lasmiditan HCl CAS: 613677-28-4
Lasmiditan hydrochloride (Lasmiditan HCl) yog ib hom tshuaj uas paub zoo txog nws lub luag haujlwm hauv kev kho mob mob taub hau loj heev rau cov neeg laus. Tsim los ua ib qho serotonin receptor agonist, tshwj xeeb tshaj yog tsom rau 5-HT1F receptor subtype, Lasmiditan HCl sawv cev rau kev nce qib tseem ceeb hauv kev kho mob taub hau vim nws txoj kev ua haujlwm tshwj xeeb thiab kev ua haujlwm zoo.
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(6-aMinopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone CAS: 613678-03-8
(6-Aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone, tseem hu ua aminopyridine methylpiperidone, yog ib qho tshuaj lom neeg uas muaj feem cuam tshuam loj heev rau kev kho mob thiab kev tshawb fawb txog tshuaj. Ua los ntawm kev sib xyaw ntawm 6-aminopicolinic acid nrog 1-methylpiperidin-4-ib, cov tshuaj no muaj cov yam ntxwv tshwj xeeb uas ua rau nws muaj peev xwm ua tshuaj thiab ua haujlwm tau ntau yam.
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(S)-(+)-3-Quinuclidinol CAS: 34583-34-1
(S)-(+)-3-Quinuclidinol, tseem hu ua quinuclidinol, yog ib qho tseem ceeb hauv kev tshawb fawb txog tshuaj lom neeg thiab tshuaj vim nws qhov tshwj xeeb ntawm cov qauv thiab kev siv ntau yam. Cov tshuaj chiral no yog los ntawm quinuclidine thiab muaj cov khoom siv tshuaj lom neeg thiab tshuaj uas tau nyiam kev mloog thoob plaws ntau yam kev tshawb fawb.
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Cov Khoom Siv Nruab Nrab CAS: 171482-05-6
Aprepitant intermediates ua lub luag haujlwm tseem ceeb hauv kev tsim tshuaj aprepitant, uas yog ib qho neurokinin-1 (NK1) receptor antagonist uas siv los tiv thaiv kev xeev siab thiab ntuav (CINV) los ntawm kev kho mob chemotherapy. Cov intermediates no yog cov khoom tseem ceeb hauv txoj kev tsim ntau kauj ruam uas ua rau aprepitant qhov kev tsim qauv kawg. Aprepitant nws tus kheej tau lees paub rau nws qhov ua tau zoo hauv kev tswj CINV, muab kev pab tseem ceeb rau cov neeg mob uas tau txais chemotherapy. Kev tsim cov aprepitant muaj ntau kauj ruam tseem ceeb, nrog rau cov intermediates ua cov khoom siv uas ua rau muaj kev tsim khoom zoo ntawm tus neeg sawv cev kho mob tseem ceeb no.
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2,4,6-TRIFLUOROBENZOYL CHLORIDE CAS: 79538-29-7
2,4,6-Trifluorobenzoyl chloride, tseem hu ua trifluorobenzoyl chloride, yog ib qho tshuaj lom neeg tseem ceeb uas muaj nqis rau nws cov kev siv ntau yam hauv kev tsim cov organic thiab cov txheej txheem kev lag luam. Tsim los ntawm kev siv chlorination ntawm 2,4,6-trifluorobenzoic acid, cov tshuaj no muaj cov yam ntxwv tshuaj lom neeg sib txawv uas ua rau nws siv dav hauv ntau qhov chaw.
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4-Chloro-6-iodoquinazoline CAS: 98556-31-1
4-Chloro-6-iodoquinazoline yog ib qho tshuaj sib xyaw nrog cov mis molecular C9H5ClIN2. Nws yog tus cwj pwm los ntawm qhov muaj cov chlorine thiab iodine atoms txuas rau lub nplhaib quinazoline. Cov tshuaj no feem ntau yog siv rau hauv kev tshawb fawb txog tshuaj thiab kev tsim cov organic vim nws muaj peev xwm siv tau hauv kev tsim cov tshuaj tshiab thiab lwm cov tshuaj lom neeg.
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(R)-3-Quinuclinol CAS: 25333-42-0
(R)-3-Quinuclinol, tseem hu ua quinuclidinol, yog ib qho tseem ceeb hauv kev tshawb fawb txog tshuaj lom neeg thiab tshuaj vim nws qhov tshwj xeeb ntawm cov qauv thiab kev siv ntau yam. Cov tshuaj chiral no yog los ntawm quinuclidine thiab ua rau pom cov khoom siv tshuaj lom neeg thiab tshuaj uas tau nyiam kev mloog thoob plaws ntau yam kev tshawb fawb.
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![(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT235.png)
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5
Cov tshuaj (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate yog ib qho organic molecule uas muaj cov yam ntxwv tshwj xeeb thiab pharmacological. Nws yog ib feem ntawm cov tshuaj morpholine, uas feem ntau siv rau hauv kev kho mob vim lawv cov dej num ntau yam.
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![(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS: 608141-42-0](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG304.png)
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS: 608141-42-0
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine yog ib hom tshuaj uas paub txog nws cov kev siv tau ntau yam hauv kev tsim cov organic thiab kev siv tshuaj. Tsim los ntawm kev sib xyaw ntawm (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone nrog ammonia lossis amine, cov tshuaj no muaj cov yam ntxwv sib txawv uas ua rau nws muaj ntau yam kev ua haujlwm thiab cov haujlwm pharmacological.
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(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine CAS: 608142-27-4
(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine yog ib hom tshuaj uas paub txog nws cov kev siv ntau yam hauv kev tsim cov organic thiab kev siv tshuaj. Tsim los ntawm kev sib xyaw ntawm 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone nrog ammonia lossis amine, cov tshuaj no muaj cov yam ntxwv tshwj xeeb uas ua rau nws muaj peev xwm ua haujlwm tau ntau yam thiab muaj peev xwm ua haujlwm pharmacological.
