Candesartan CAS: 139481-59-7 Chaw Tsim Khoom

Candesartan yog ib qho angiotensin II receptor I (AT1) antagonist, IC50s = 1.12 thiab 2.86 nM rau bovine adrenal cortex thiab rabbit aorta feem. Xaiv inhibits angiotensin II-induced contraction ntawm rabbit aortic strips tsis muaj kev cuam tshuam rau contraction los ntawm lwm yam tshuaj xws li norepinephrine, KCl, serotonin, PGF2α lossis endothelin.

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Daim Ntawv Thov thiab Cov Nyhuv

Candesartan yog ib qho tshuaj AT1 (angiotensin II receptor 1) uas xaiv tau. Kev tawm tsam ntawm angiotensin receptors ua rau vasoconstriction thiab aldosterone tsim tawm, ua rau cov dej thiab sodium concentration hauv cov ntshav plasma tsawg dua. Muaj cov txiaj ntsig tiv thaiv kab mob ntshav siab hauv cov qauv tsiaj. Siv rau kev kho mob plawv tsis ua haujlwm, ua ib qho tshuaj tiv thaiv kab mob ntshav siab. Candesartan tsis cuam tshuam rau kev muaj sia nyob lossis kev loj hlob ntawm cov hlwb tab sis ua rau muaj kev qhia tawm ntawm VEGF thiab interleukin-8 hauv cov kab lis kev cai ntawm KU-19-19 hlwb. Candesartan (0.1 nM) tuaj yeem txo qhov kev teb rov qab rau angiostensin II li ntawm 50%.

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Cov Lus Qhia Ntxiv:

Kev sau ua ke	C24H20N6O3
Kev Ntsuas	99%
Qhov tsos	Hmoov dawb
CAS Nr.	139481-59-7
Ntim khoom	1KG 25KG
Lub Neej Txee	2 xyoos
Kev Khaws Cia	Khaws cia rau qhov chaw txias thiab qhuav
Daim Ntawv Pov Thawj	ISO.