Candesartan CAS: 139481-59-7 Chaw tsim tshuaj paus

Candesartan yog angiotensin II receptor I (AT1) antagonist, IC50s = 1.12 thiab 2.86 nM rau bovine adrenal cortex thiab luav aorta feem.Selectively inhibits angiotensin II-induced contraction ntawm luav aortic strips uas tsis muaj kev cuam tshuam ntawm contraction induced los ntawm lwm tus neeg sawv cev. , KCl, serotonin, PGF2α lossis endothelin.

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Candesartan yog ib qho kev xaiv AT1 (angiotensin II receptor 1) antagonist.Kev tawm tsam ntawm angiotensin receptors inhibits vasoconstriction thiab tsim cov aldosterone, ua rau txo qis hauv dej thiab sodium concentration hauv ntshav plasma.Exhibits antihypertensive teebmeem hauv cov qauv tsiaj.Siv rau hauv kev kho mob ntawm congestive plawv tsis ua hauj lwm, raws li antihypertensive.Candesartan tsis cuam tshuam rau cell viability lossis proliferation tab sis nce kev qhia ntawm VEGF thiab interleukin-8 hauv kab lis kev cai nruab nrab ntawm KU-19-19 hlwb.Candesartan (0.1 nM) tuaj yeem txo qhov kev cog lus siab tshaj plaws rau angiostensin II los ntawm kwv yees li 50%.

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Kev sib xyaw	C24H20N6O3
Assay	99%
Qhov tshwm sim	Dawb hmoov
CAS Nr.	139481-59-7
Ntim	1 KG 25 KG
Txee lub neej	2 xyoo
Cia	Khaws rau hauv qhov chaw txias thiab qhuav
Daim ntawv pov thawj	ISO.