2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS: 76204-02-9 Duab Tshwj Xeeb

2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM NTSEV CAS: 76204-02-9

2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium ntsev yog ib qho tshuaj lom neeg uas feem ntau siv rau hauv kev kuaj mob thiab kev tshawb fawb. Nws yog ib qho fluorescent labeled derivative ntawm sialic acid, ib hom carbohydrate molecule pom nyob rau ntawm qhov chaw ntawm cov cell.

Cov tshuaj no yog siv ua lub substrate rau cov enzymes hu ua neuraminidases, uas ua haujlwm los tshem tawm cov sialic acid residues ntawm glycoproteins thiab glycolipids. Thaum cov enzymes no ua haujlwm rau 2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium ntsev, nws tso tawm cov khoom fluorescent hu ua 4-methylumbelliferone.

Qhov fluorescence uas tsim los ntawm cov tshuaj no tuaj yeem ntsuas thiab ntsuas tau, muab cov ntaub ntawv hais txog kev ua haujlwm ntawm cov enzymes neuraminidase. Qhov no yog qhov tshwj xeeb tshaj yog pab tau rau kev kawm txog ntau yam kab mob thiab tej yam mob uas cuam tshuam nrog aberrant sialic acid metabolism.

Cov tshuaj no kuj siv rau kev kuaj mob, xws li kev kuaj pom cov kab mob viral uas muaj neuraminidase ua haujlwm. Hauv cov kev sim no, cov tshuaj no siv los txheeb xyuas qhov muaj cov kab mob viral tshwj xeeb lossis ntsuas qhov ua tau zoo ntawm cov tshuaj neuraminidase inhibitors hauv kev kho mob antiviral.

Txiav txim los yog Thov Kev Hais Nqe

Cov Lus Qhia Txog Khoom

Cov Cim Npe Khoom

Daim Ntawv Thov thiab Cov Nyhuv

Kev Ntsuas Kev Ua Haujlwm ntawm Neuraminidase: Cov tshuaj no feem ntau siv los ntsuas kev ua haujlwm ntawm cov enzymes neuraminidase hauv cov qauv kuaj mob. Los ntawm kev saib xyuas qhov fluorescence tsim tawm, cov kws tshawb fawb tuaj yeem txiav txim siab qib ntawm kev ua haujlwm ntawm neuraminidase, uas tuaj yeem pab hauv kev kawm txog ntau yam kab mob thiab tej yam mob.

Kev Tshawb Pom Kab Mob Viral: Ntau yam kab mob viral, suav nrog mob khaub thuas, muaj kev ua haujlwm ntawm neuraminidase. Cov tshuaj no siv tau los nrhiav thiab ntsuas qhov muaj cov kab mob viral tshwj xeeb los ntawm kev ntsuas kev ua haujlwm ntawm fluorescent. Nws muaj txiaj ntsig zoo rau kev ntsuam xyuas qhov ua tau zoo ntawm cov tshuaj neuraminidase inhibitors hauv kev kho mob antiviral.

Kev Tshuaj Xyuas Glycosylation: Sialic acid yog ib qho tseem ceeb ntawm glycoproteins thiab glycolipids. Los ntawm kev siv 2'-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium ntsev rau hauv kev sim, cov kws tshawb fawb tuaj yeem nkag siab txog sialic acid metabolism, glycosylation qauv, thiab cov txheej txheem physiological cuam tshuam.

Kev Tshawb Nrhiav Tshuaj: Cov tshuaj neuraminidase inhibitors yog ib pawg tshuaj siv rau kev kho mob ntawm cov kab mob viral. Cov tshuaj no siv tau rau hauv kev tshawb nrhiav tshuaj, pab cov kws tshawb nrhiav txheeb xyuas thiab soj ntsuam cov tshuaj uas ua rau neuraminidase ua haujlwm.

Khoom Ntim:

Cov Lus Qhia Ntxiv:

Kev sau ua ke	C21H26NNaO11
Kev Ntsuas	99%
Qhov tsos	Hmoov dawb
CAS Nr.	76204-02-9
Ntim khoom	Me me thiab ntau
Lub Neej Txee	2 xyoos
Kev Khaws Cia	Khaws cia rau qhov chaw txias thiab qhuav
Daim Ntawv Pov Thawj	ISO.