2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-ib CAS:1044871-04-6

Qhov siv tau ntau yam ntawm 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one yog nyob rau hauv nws cov peev xwm siv rau hauv kev tshawb fawb thiab kev tsim kho tshuaj. Ua ib qho tseem ceeb nruab nrab, cov tshuaj no pab txhawb rau kev tsim cov tshuaj tshiab thiab cov tshuaj pharmacologically active. Cov kws tshawb fawb siv nws cov yam ntxwv tshwj xeeb los tshawb nrhiav nws lub luag haujlwm hauv kev tsim cov tshuaj kho mob rau ntau yam kab mob, uas ua rau muaj kev tsim cov khoom tshuaj tshiab nrog kev ua haujlwm zoo dua thiab cov khoom pharmacokinetic zoo dua. Ntxiv mus, cov tshuaj no yuav pom siv rau hauv kev kho mob chemistry rau kev tsim thiab kev tsim cov tshuaj nrog cov haujlwm tshwj xeeb. Nws cov yam ntxwv ntawm cov qauv ua rau nws tsim nyog rau kev tshawb nrhiav kev sib raug zoo ntawm cov qauv thiab kev ua haujlwm, pab txheeb xyuas cov tshuaj lead uas muaj peev xwm rau kev tsim tshuaj. Tsis tas li ntawd, nws tuaj yeem ua lub hauv paus tseem ceeb rau kev tsim cov tshuaj organic sib txawv, pab txhawb rau kev nthuav dav ntawm qhov chaw tshuaj muaj rau kev tshawb pom tshuaj thiab kev tsim cov tshuaj. Zuag qhia tag nrho, 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one muaj peev xwm tseem ceeb hauv kev tsav tsheb kev nce qib hauv kev tshawb fawb txog tshuaj, tshuaj lom neeg, thiab kev tsim cov tshuaj sib xyaw ua ke, tso nws ua ib qho khoom muaj nqis hauv kev tshawb fawb thiab kev tsim kho tshiab hauv cov chaw muag tshuaj thiab tshuaj lom neeg.