β-Nicotinamide Mononucleotide CAS: 1094-61-7

Nicotinamide mononucleotide (NMN), ib yam khoom ntawm NAMPT reaction thiab ib qho tseem ceeb NAD+ intermediate, ua kom cov glucose intolerance zoo dua los ntawm kev kho NAD+ cov qib hauv HFD-induced T2D nas. NMN kuj tseem ua rau hepatic insulin rhiab heev thiab rov qab kho cov gene expression ntsig txog oxidative stress, inflammatory response, thiab circadian rhythm, ib feem los ntawm SIRT1 activation. NMN yog siv rau kev kawm txog binding motifs hauv RNA aptamers thiab ribozyme activation processes uas muaj β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

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β-Nicotinamide mononucleotide (NMN) yog siv los kawm txog cov qauv khi hauv RNA aptamers thiab cov txheej txheem ua kom ribozyme uas muaj β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments. NMN yog nucleotide uas tau los ntawm ribose thiab nicotinamide. Niacinamide (nicotinamide,) yog ib qho derivative ntawm vitamin B3, tseem hu ua niacin.) Raws li biochemical precursor ntawm NAD +, nws yuav pab tau rau kev tiv thaiv pellagra.
β-Nicotinamide mononucleotide yog ib qho nruab nrab hauv biosynthesis ntawm nicotinamide adenine dinucleotide (NAD +). Nicotinamide phosphoribosyltransferase (Nampt) catalyzes qhov condensation ntawm nicotinamide nrog 5-phosphoribosyl-1-pyrophosphate los tsim β-NMN, uas tom qab ntawd hloov mus rau NAD + los ntawm β-NMN adenyltransferase. Ntawm 50-100 μM, β-NMN tau siv los txhim kho NAD biosynthesis thiab glucose-stimulated insulin secretion hauv Nampt +/- nas qauv ntawm metabolic kab mob, qhia txog lub luag haujlwm rau Nampt hauv β cell ua haujlwm.

Qauv Khoom

Khoom Ntim:

Cov Lus Qhia Ntxiv:

Kev sau ua ke	C11H15N2O8P
Kev Ntsuas	99%
Qhov tsos	Hmoov dawb
CAS Nr.	1094-61-7
Ntim khoom	25KG
Lub Neej Txee	2 xyoos
Kev Khaws Cia	Khaws cia rau qhov chaw txias thiab qhuav
Daim Ntawv Pov Thawj	ISO.