Uridine,2′-deoxy-5-ethynyl- CAS: 61135-33-9

5-ethynyl-2′-deoxyuridine (EdU) yog ib qho nucleoside analog uas feem ntau siv rau hauv kev tshawb fawb txog molecular biology thiab cell biology. Nws feem ntau siv los cim thiab nrhiav DNA tshiab uas tau tsim hauv cov cell uas muaj sia nyob los ntawm cov txheej txheem hu ua "click chemistry." Cov txheej txheem no tso cai rau kev pom thiab kev ntsuas ntawm DNA replication thiab cell proliferation. EdU tau dhau los ua lwm txoj hauv kev nrov rau cov thymidine analog bromodeoxyuridine (BrdU) ib txwm muaj vim nws sib xws nrog fluorescence microscopy thiab tsis muaj cov kauj ruam DNA denaturation hnyav thaum lub sijhawm nrhiav. Tsis tas li ntawd, EdU cov qauv tshuaj tso cai rau kev nrhiav tshwj xeeb thiab ua haujlwm tau zoo, ua rau nws yog ib qho cuab yeej muaj txiaj ntsig rau kev kawm txog DNA synthesis thiab cell cycle dynamics.