Trt-Gly-OH CAS: 5893-05-0

Bz-His-OMe ua lub luag haujlwm tseem ceeb hauv kev tsim cov peptide, ua lub hauv paus tseem ceeb rau kev tsim cov peptides nrog cov yam ntxwv tshwj xeeb thiab kev ua haujlwm. Pawg tiv thaiv benzyl ua kom ntseeg tau tias cov histidine residue tseem tsis hloov pauv thaum lub sijhawm tsim cov peptide, ua rau muaj kev sib dhos peptide meej thiab tswj tau. Tsis tas li ntawd, qhov muaj cov pab pawg methyl ester cuam tshuam rau cov tshuaj reactivity thiab hydrophobic sib cuam tshuam ntawm peptide, ua rau nws muaj txiaj ntsig zoo rau kev tsim cov peptides nrog kev txhim kho membrane permeability lossis cov peev xwm tshwj xeeb. Hauv kev tsim tshuaj, cov tshuaj no tuaj yeem siv los tsim cov tshuaj peptide-based nrog kev ruaj khov zoo dua thiab bioavailability, uas ua rau muaj kev kho mob zoo dua. Ntxiv rau nws lub luag haujlwm hauv kev tsim peptide, Bz-His-OMe pom daim ntawv thov hauv proteomics thiab kev tshawb fawb biochemical, qhov twg nws tuaj yeem siv los kawm txog kev sib cuam tshuam ntawm cov protein-protein, tshawb nrhiav cov haujlwm enzymatic, thiab tshawb nrhiav cov kev hloov pauv ntawm cov protein pH. Nws cov qauv tsim tshwj xeeb tso cai rau cov kws tshawb fawb los tshawb nrhiav qhov nyuaj ntawm cov txheej txheem cellular thiab cov txheej txheem kab mob, pab txhawb rau kev nce qib hauv kev nkag siab txog kev noj qab haus huv thiab pathology. Cov tshuaj no muaj ntau yam thiab sib haum nrog ntau yam kev sim ua rau nws yog ib qho tseem ceeb rau kev daws qhov teeb meem ntawm cov kab mob hauv lub cev thiab tsim cov kev cuam tshuam rau ntau yam mob. Hauv kev xaus, Bz-His-OMe yog ib qho cuab yeej muaj txiaj ntsig rau cov kws tshawb fawb hauv kev tsim cov peptide, kev tsim tshuaj, thiab kev tshawb fawb txog biochemical, muab lub peev xwm los kho cov peptides nrog cov khoom tshwj xeeb thiab daws cov txheej txheem tseem ceeb ntawm cov txheej txheem hauv lub cev, yog li pab txhawb rau kev nce qib hauv kev kho mob thiab biotechnology.