Sodium Alpha-Ketoisocaproate CAS: 4502-00-5 Chaw Tsim Khoom

Sodium Alpha-Ketoisocaproate yog ib qho leucine metabolite uas paub tias ua rau muaj insulin secretion los ntawm β hlwb ntawm pancreas. Kev txhaj tshuaj ntawm aα-Ketoisocaproate hauv plab pom tias ua rau zoo dua, endotoxemic mob. Cov ketone lub cev tau los ntawm nws qhov kev hloov pauv, yuav ua haujlwm ua lub zog. Kev sib sau ua ke ntawm α-Ketoisocaproic acid yog tus yam ntxwv hauv branched chain ketoaciduria, uas yog tshwm sim vim tsis muaj branched chain L-2-keto acid dehydrogenase activity. α-Ketoisocaproic acid ua rau muaj kev sib cais hauv oxidative phosphorylation reaction thiab ua haujlwm ua tus metabolic inhibitor ntawm α-ketoglutarate dehydrogenase. Yog li, ua rau muaj qhov tsis zoo hauv mitochondrial homeostasis, pom hauv branched chain ketoaciduria.