Sodium Alpha-Ketoisocaproate CAS: 4502-00-5 Chaw tsim tshuaj paus

Sodium Alpha-Ketoisocaproate yog leucine metabolite uas paub tias ua rau cov tshuaj insulin tso tawm los ntawm βcells ntawm pancreas.Enteral infusion ntawm aα-Ketoisocaproate yog pom muaj rau ameliorate, endotoxemic mob.Qhov tshwm sim ntawm ketone lub cev tau txais los ntawm nws qhov kev hloov pauv, tuaj yeem ua haujlwm ua lub zog.Kev sib sau ntawm α-Ketoisocaproic acid yog tus cwj pwm hauv cov saw hlau ketoaciduria, uas yog tshwm sim vim tsis muaj cov saw hlau L-2-keto acid dehydrogenase kev ua haujlwm.α-Ketoisocaproic acid ua rau dissociation hauv oxidative phosphorylation cov tshuaj tiv thaiv thiab ua raws li metabolic inhibitor ntawm α-ketoglutarate dehydrogenase.Yog li, ua rau muaj qhov tsis xws luag hauv mitochondrial homeostasis, pom nyob rau hauv ceg saw ketoaciduria.