R-(+)-alpha-Lipoic acid CAS:1200-22-2 Chaw Tsim Khoom Siv

R-(+)-α-Lipoic acid tau pom tias ua rau pyruvate oxidation ntau ntxiv thaum tshem tawm cov roj fatty acid oxidation hauv cov hepatocytes nas. Cov teebmeem no ua rau R-(+)-α-Lipoic acid yog ib txoj kev kho mob zoo rau kev kho mob ntshav qab zib hom II. Nws yog ib qho tshuaj antioxidant biological nrog cov haujlwm prooxidant, nws lub peev xwm kho tau raug tshawb nrhiav dav dav, piv txwv li hauv kev kho mob Alzheimer's kab mob. α-Lipoic acid tau siv los ua tus qauv siv rau kev tshuaj xyuas α-lipoic acid hauv tib neeg cov ntshav los ntawm kev siv cov kua chromatography ua haujlwm siab ua ke nrog electron capture detector (HPLC-ECD), hauv ntau yam khoom noj matrices thiab cov khoom noj khoom haus ntxiv los ntawm HPLC ua ke nrog coulometric electrode array detector (CEAD) nrog rau electrospray ionization mass spectrometer (ESI-MS). Nws tuaj yeem siv los ua tus qauv siv rau kev txiav txim siab ntawm α-lipoic acid hauv tib neeg cov zis los ntawm isocratic reversed-phase HPLC thiab hauv α-lipoic acid capsules los ntawm HPLC nrog chemiluminescence detection.