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Venlafaxine CAS: 93413-69-5
Venlafaxine yog ib qho tshuaj tiv thaiv kev nyuaj siab ntawm serotonin thiab norepinephrine reuptake inhibitor (SNRI) chav kawm.Cov tshuaj no yog thawj zaug tsim los ntawm Wyeth hauv 19Chemicalbook93 thiab tam sim no ua lag luam los ntawm Pfizer.Cov tshuaj no tau pom zoo rau kev kho mob ntawm kev nyuaj siab loj (MDD), kev ntxhov siab dav dav (GAD), thiab kev nyuaj siab cuam tshuam nrog kev ntxhov siab.
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Bet-Nicotinamide Mononucleotide CAS: 1094-61-7
Nicotinamide mononucleotide (NMN), ib yam khoom ntawm NAMPT cov tshuaj tiv thaiv thiab ib qho tseem ceeb NAD + nruab nrab, ameliorates qabzib intolerance los ntawm restore NAD + qib hauv HFD-induced T2D nas.NMN kuj tseem txhim kho lub siab insulin rhiab heev thiab rov kho cov noob qhia ntsig txog oxidative kev nyuaj siab, inflammatory teb, thiab circadian atherosclerosis, ib nrab ntawm SIRT1 ua kom.NMN yog siv los kawm txog kev sib txuas motifs nyob rau hauv RNA aptamers thiab ribozyme activation txheej txheem uas muaj β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.
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Bet-Nicotinamide Adenine Dinucleotide CAS: 53-84-9
β-Nicotinamide adenine dinucleotide (NAD) yog oxidized daim ntawv ntawm β-Nicotinamide Adenine Dinucleotide.Nws tshwm sim raws li anion nyob rau hauv ib txwm physio-logic tej yam kev mob.Nws muaj feem cuam tshuam nrog deamido-NAD zwitterion.Nws yog lub hauv paus conjugate ntawm NAD (+).Nws tau pom dav dav hauv qhov xwm txheej thiab koom nrog ntau cov tshuaj tiv thaiv enzymatic uas nws ua haujlwm raws li cov khoom siv hluav taws xob los ntawm kev hloov pauv oxidized (NAD +) thiab txo qis (NADH).
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β-Nicotinamide Adenine Dinucleotide txo daim ntawv CAS: 606-68-8
β-Nicotinamide adenine dinucleotide (NAD +) thiab β-Nicotinamide adenine dinucleotide, txo qis (NADH) suav nrog coenzyme redox khub (NAD +: NADH) koom nrog ntau yam enzyme catalyzed oxidation txo cov tshuaj tiv thaiv.Ntxiv rau nws txoj haujlwm redox, NAD + / NADH yog tus pub ntawm ADP-ribose units hauv ADP-ribosyltransferases; poly (ADP-ribose) polymerases) cov tshuaj tiv thaiv thiab ua ntej ntawm cyclic ADP-ribose (ADP-ribosyl cyclases) .
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Bet-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt, txo daim ntawv CAS: 2646-71-1
NADPH yog qhov txo qis ntawm coenzyme NADP +;siv nyob rau hauv cov tshuaj anabolic xws li lipid thiab nucleic acid synthesis, uas yuav tsum tau NADPH raws li ib tug txo tus neeg sawv cev.NADPH, Tetrasodium ntsev yog ib tug ubiquitous coenzyme uas ua raws li ib tug electron pub nyob rau hauv ntau yam kev tshwm sim siv dehydrogenase thiab reductase enzymes.Nws yog tsim los ntawm kev txo cov electron txais NADP +.Txoj hauv kev lom neeg hauv qab no koom nrog NADPH: tsim cov carbohydrate los ntawm CO2 thaum lub sij hawm photosynthesis, kev saib xyuas cov qib siab ntawm glutathione hauv erythrocytes, txo cov thioredoxin.
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Thio-Nicotinamide Adenine Dinucleotide (Thio-NAD) CAS: 4090-29-3
Thionicotinamide adenine dinucleotide yog ib qho analog ntawm NAD.Kev siv Thio-NAD hloov NAD ua lub substrate rau NAD (+)-kev siv cov enzymes yog qhov zoo dua vim tias daim ntawv txo qis ntawm Thio-NAD nthuav tawm ntau qhov kev nqus ntawm 405 nM, feem ntau muaj wavelength ntawm microplate nyeem.
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Bet-Nicotinamide Adenine Dinucleotide Phosphate Monosodium Salt CAS: 1184-16-3
Nicotinamide adenine dinucleotide phosphate, abbreviated NADP + los yog, nyob rau hauv cov laus sau ntawv, TPN (triphosphopyridine nucleotide), yog ib tug cofactor siv nyob rau hauv cov tshuaj anabolic, xws li Calvin voj voog thiab lipid thiab nucleic acid syntheses, uas yuav tsum tau NADPH raws li ib tug txo tus neeg sawv cev ('hydrogen source). ').Nws yog siv los ntawm txhua hom cellular lub neej.
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Ciclopirox Ethanolamine CAS: 41621-49-2 Chaw tsim tshuaj paus
Ciclopirox ethanolamine yog ib tug dav spectrum antigfungal tus neeg saib xyuas, nws kuj muaj antibacterial kev ua si tawm tsam ntau Gram-positive thiab Gram-negative kab mob, thiab muaj anti-inflammatory zog.Nws yog siv los kho cov kab mob fungal ntawm daim tawv nqaij ntawm tus ntsia thawv kab mob.
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Desvenlafaxine Succinate CAS: 386750-22-7
Desvenlafaxine Succinate yog dual serotonin thiab norepinephrine reuptake inhibitor (SNRI) uas tau pom zoo rau kev kho mob ntawm kev nyuaj siab loj (MDD) hauv Tebchaws Meskas hauv xyoo 2008. Txhawm rau txhim kho qhov ua tau zoo thiab kev nyab xeeb profile ntawm venlafaxine, Wyeth nrhiav thiab tsim ib qho ntawm cov metabolites loj ntawm venlafaxine, uas yog O-desmethyl metabolite (desvenlafaxine).
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Doxazosin Mesylate CAS: 77883-43-3 Chaw tsim tshuaj paus
Doxazosin mesylate yog quinazoline compound uas yog ib qho kev xaiv inhibitor ntawm alpha1 subtype ntawm alpha adrenergic receptors.Doxazosin mesylate yog ib tiam tshiab ntawm quinazolone α1 receptor blocker tsim los ntawm lub tuam txhab Pfizer (Tebchaws Asmeskas), Nws muaj ib nrab-lub neej ntev, ua rau nws cov teebmeem ntawm dilating cov hlab ntsha, txo cov vascular kuj thiab txo cov ntshav siab los ntawm kev thaiv cov hlab ntsha. ib 1 receptor.Nws tau raug pom zoo rau txawv teb chaws raws li thawj-kab kho mob tshuaj ntawm anti-hypertension thiab kev kho mob ntawm prostate kab mob.
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L-Isoleucine CAS: 73-32-5 Chaw tsim tshuaj paus
L-Isoleucine, tseem hu ua Isoleucine, yog ib qho amino acid uas yog isomer ntawm leucine.Nws yog ib qho tseem ceeb hauv hemoglobin synthesis thiab tswj cov ntshav qab zib thiab lub zog theem.L-Isoleucine yog ib qho isomer ntawm L-leucine thiab yog ib qho tseem ceeb amino acid.Nws yog synthesized los ntawm threonine thiab yog ib tug branched-chain hydrophobic amino acid.
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Captopril CAS: 62571-86-2 Chaw tsim tshuaj paus
Captopril yog qhov kev tshawb fawb tshaj plaws ntawm angiotensin-hloov enzyme inhibitors tau npaj ua cov tshuaj tiv thaiv kab mob siab.Nws blocks angiotensin-hloov enzyme, uas inhibits tsim ntawm angiotensin II thiab relieves nws vasoconstricting nyhuv ntawm arterial thiab venous hlab ntsha.Zuag qhia tag nrho vascular peripheral nro yog txo, uas ua rau txo qis ntawm arterial siab.
