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N-Acetyl-D-Glucosamine CAS: 7512-17-6 Chaw Tsim Khoom Siv
N-Acetyl-D-Glucosamine yog N-acetyl derivative ntawm glucosamine. Chemically nws yog ib qho amide ntawm glucosamine thiab acetic acid. Ib qho N-acetlyglucosamine moiety txuas nrog serine lossis threonine residues ntawm nuclear thiab cytoplasmic proteins -O-GlcNAc, yog ib qho kev hloov pauv protein tom qab txhais lus. O-GlcNAc hloov kho cov proteins koom nrog kev paub txog cov khoom noj khoom haus ntawm cov cellular ib puag ncig thiab kho cov haujlwm ntawm cov cellular proteins raws li. O-GlcNAc tswj cov lus teb cellular rau cov tshuaj hormones xws li insulin, pib tiv thaiv kev ntxhov siab, modulates lub peev xwm ntawm lub cell kom loj hlob thiab faib, thiab tswj cov gene transcription. Hauv tib neeg, nws muaj nyob rau hauv daim tawv nqaij, pob txha mos thiab cov hlab ntsha ua ib feem ntawm hyaluronic acid, thiab cov pob txha nqaij, cornea thiab aorta ua ib feem ntawm keratan sulfate.
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Creatine Pyruvate CAS: 55965-97-4 Chaw Tsim Khoom Siv
Creatine Pyruvate yog ib qho tshuaj uas muaj Creatine thiab pyruvic acid thiab siv los ntawm cov neeg tsim lub cev ua cov tshuaj ntxiv kom tau txais cov txiaj ntsig ergogenic thiab yaj tag nrho hauv dej. Hauv nws daim ntawv sib xyaw Creatine Pyruvate yaj tau 10 npaug ntau dua li hauv lawv daim ntawv ib tus neeg. Cov kev tshawb fawb hauv tsev kho mob tau qhia tias Pyruvate txo cov rog hauv lub cev yam tsis cuam tshuam rau cov protein ntawm cov leeg nqaij, uas yog ib qho tseem ceeb hauv kev ua tiav cov leeg nqaij ntshiv. Cov tshuaj ntxiv Creatine Pyruvate yog kev txhawb nqa kev noj haus zoo tshaj plaws rau cov neeg ncaws pob uas tab tom nrhiav kev ua kom cov leeg nqaij ua haujlwm tau zoo tshaj plaws thiab ua siab ntev hauv cov kev tawm dag zog siab.
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Vitamin A Palmitat CAS: 79-81-2 Chaw Tsim Khoom Siv
Retinyl palmitate yog ib hom tshuaj hu ua retinoids, uas zoo ib yam li vitamin A. Nws muaj txiaj ntsig zoo rau kev pom kev, daim tawv nqaij thiab kev tiv thaiv kab mob, tiv thaiv kev loj hlob ntawm cov cell thiab tiv thaiv mob qog noj ntshav. Nws yog ib qho khoom noj tseem ceeb thiab yog ib qho tshuaj kho mob. All-trans-retinyl palmitate yog ib qho all-trans-retinyl ester tau los ntawm kev sib xyaw ua ke ntawm pawg carboxy ntawm palmitic (hexadecanoic acid) nrog pawg hydroxy ntawm all-trans-retinol. Nws yog siv rau hauv cov khoom siv pleev kom zoo nkauj los kho ntau yam kab mob ntawm daim tawv nqaij xws li pob txuv, tawv nqaij laus, wrinkles, cov pob dub, thiab tseem tiv thaiv kab mob psoriasis. Nws muaj lub luag haujlwm ua Escherichia coli metabolite, ib qho tib neeg xenobiotic metabolite thiab ib qho antioxidant. Nws yog retinyl palmitate thiab all-trans-retinyl ester. Nws muaj feem cuam tshuam nrog all-trans-retinol.
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Benfotiamine CAS: 22457-89-2 Chaw Tsim Khoom
S-Benzoylthiamine O-monophosphate (Benfotiamine) yog ib qho amphiphilic S-acyl thiamine derivative. Nws yog ib qho vitamin uas yaj tau hauv lipid. Benfotiamine muaj ib lub nplhaib thiazole. Benfotiamine muaj bioavailability ntau dua li thiamine.
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Collagen Hydrolyzed CAS: 92113-31-0 Chaw Tsim Khoom Chaw Tsim Khoom
Hydrolyzed collagen tseem hu ua hydrolyzed collagen. Hydrolyzed collagen yog ib hom khoom collagen tshiab, uas yog tsim los ntawm collagen lossis collagen-nplua nuj cov peev txheej. Ntxiv nrog rau cov yam ntxwv amino acid muaj pes tsawg leeg ntawm collagen (kwv yees li 30% ntawm tag nrho cov amino acid residues yog glycine), nws kuj muaj 15-30% ntawm ob qho amino acids uas tsis tshua pom muaj nyob rau hauv lwm cov protein, proline thiab 4-hydroxyproline (Ntxiv rau acid), nws kuj muaj cov yam ntxwv ntawm qhov hnyav molecular me me, thiab cov khoom sib xyaw ua ke feem ntau yog tsim los ntawm cov peptides me me nrog qhov hnyav molecular tsawg dua 3000.
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Natural Vitamin E CAS: 59-02-9 Chaw Tsim Khoom Siv
Cov roj Vitamin E yog cov vitamin uas yaj tau hauv roj, tseem hu ua tocopherol. Nws yog ib qho ntawm cov tshuaj antioxidants tseem ceeb tshaj plaws. Nws yog cov roj-soluble organic solvents xws li ethanol, thiab insoluble hauv dej, cua sov, acid ruaj khov, base-labile. Nws yog rhiab rau oxygen tab sis tsis rhiab rau cua sov. Thiab cov haujlwm ntawm vitamin E yog qis dua frying. α-Tocopherol yog synthesized los ntawm γ-tocopherol los ntawm kev ua ntawm enzyme γ-tocopherol methyltransferase. Nws yog daim ntawv tseem ceeb ntawm Vitamin E hauv tib neeg cov ntshav. Nws muaj nyob rau hauv cov roj noob paj noob hlis.
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Curcumin (turmeric) 95% CAS: 458-37-7 Chaw Tsim Khoom Siv
Curcumin yog cov xim daj tseem ceeb hauv turmeric thiab curry thiab muaj cov tshuaj antioxidant, anti-inflammatory, thiab antitumor. Nws inhibits nitric oxide (NO) ntau lawm (IC50 = 6 μM) thiab txo cov inducible nitric oxide synthase (iNOS) kev ua haujlwm hauv LPS-stimulated RAW 264.7 hlwb. Curcumin inhibits kev tso tawm ntawm histamine thiab cov cytokines inflammatory TNF-α, IL-1β, IL-6, thiab IL-8 los ntawm HMC-1 mast hlwb. Hauv vivo, curcumin txo cov theem serum ntawm histamine thiab TNF-α, inhibits histopathological hloov pauv ntawm lub qhov ntswg mucosa, thiab txo cov naj npawb ntawm kev txham thiab kev sib txhuam ntawm lub qhov ntswg hauv tus qauv nas ntawm ovalbumin-induced rhinitis.
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Vitamin B1 (Thiamine Hydrochloride) CAS: 67-03-8 Chaw Tsim Khoom Siv
Thiamine Hydrochloride yog cov hydrochloride ntsev ntawm thiamine (vitamin B1), ib qho vitamin tseem ceeb rau kev ua haujlwm ntawm lub cev, kev loj hlob ntawm cov hlwb, kev xa cov hlab ntsha thiab kev tsim cov acetylcholine. Vitamin B1 pab tiv thaiv ntau yam teeb meem kev noj qab haus huv suav nrog kev puas tsuaj rau lub plawv.
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Hydroxycobalamin HCL CAS: 78091-12-0 Chaw Tsim Khoom Siv
Hydroxycobalamin (ohcbl, lossis B12a) yog ib hom vitamin B12 ntuj, lossis ib qho ntawm cov vitamin B12 chav kawm. Nws yog ib tug tswv cuab tseem ceeb ntawm pawg cobalamine. Ntau cov kab mob uas tsim cov vitamins lag luam tsim cov vitamin B12 hauv daim ntawv ntawm hydroxycobalamin. Hydroxycobalamin yog xim liab tsaus. Vitamin B12 hauv tib neeg lub cev feem ntau tsis muaj nyob hauv daim ntawv ntawm hydroxycobalamin. Txawm li cas los xij, hauv tib neeg, hydroxycobalamin yooj yim hloov mus ua ib daim ntawv coenzyme ntawm vitamin B12. Cov khoom siv tshuaj hydroxycobalamin yog nws cov tshuaj txhaj tshuaj, uas yog siv los kho cov vitamin tsis txaus thiab cyanide lom (vim nws sib xws nrog cyanide ions).
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Collagen II CAS: 9064-67-9 Chaw Tsim Khoom
Collagen yog cov khoom tseem ceeb tshaj plaws ntawm cov extracellular matrix uas muaj ntau cov protein fibrous hauv txhua qhov chaw siab dua. Nws feem ntau pom muaj nyob rau hauv cov ntaub so ntswg fibrous xws li daim tawv nqaij, ligament thiab tendon hauv daim ntawv ntawm elongated fibrils thiab kuj muaj ntau nyob rau hauv cornea, cov hlab ntsha, pob txha, cartilage, intervertebral disc thiab plab hnyuv. Cov no yog cov protein ntau tshaj plaws hauv cov tsiaj txhu uas tsim ntau dua 30% ntawm tag nrho cov protein hauv lub cev tsiaj.
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Nicotinamide Riboside (Chloride) CAS: 23111-00-4 Chaw Tsim Khoom Siv
Nicotinamide Riboside Chloride yog cov ntsev chloride ntawm nicotinamide riboside (NR). NR yog ib daim ntawv tshiab pyridine-nucleoside ntawm vitamin B3 uas ua haujlwm ua tus precursor rau nicotinamide adenine dinucleotide (NAD) lossis NAD +. Nicotinamide riboside chloride yog ib daim ntawv siv lead ua ntawm Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride ua rau NAD [+] theem nce thiab ua kom SIRT1 thiab SIRT3 ua haujlwm, ua rau muaj kev ua haujlwm ntawm oxidative thiab tiv thaiv kev noj zaub mov uas muaj roj ntau. Nicotinamide riboside chloride siv rau hauv cov tshuaj noj.
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D-Fructose 1,6-Disphosphate Trisodium Ntshav CAS: 38099-82-0
Fructose-1,6-biphosphate (F1,6P) yog ib qho glycolytic intermediate uas tsim los ntawm kev hloov pauv ntawm phosphate los ntawm ATP mus rau fructose-6-phosphate los ntawm cov enzyme phosphofructokinase. Fructose-1,6-biphosphate, nrog rau fructose-2,6-biphosphate, hloov kho qhov kev ua haujlwm ntawm phosphofructokinase-1 (PFK-1), cov kauj ruam txwv tus nqi hauv glycolysis. Thaum lub sijhawm glycolysis, aldolase faib Fructose-1,6-biphosphate ua dihydroxacetone phosphate (DHAP) thiab glyceraldehyde phosphate. Fructose-1,6-biphosphate kuj yog ib qho allosteric activator ntawm M2 isoform ntawm Pyruvate Kinase (PK-M2), daim ntawv tseem ceeb ntawm pyruvate kinase hauv cov hlwb qog noj ntshav.
