N-methyl-2,2,2-trifluoroacetamide CAS: 815-06-5

N-Methyl-2,2,2-trifluoroacetamide (NMTFA) yog tus cwj pwm los ntawm nws cov qauv molecular, uas suav nrog trifluoromethyl pawg (-CF3) txuas rau acetamide backbone (-CONHCH3). Cov qauv no muab kev ruaj khov thiab kev ua haujlwm tseem ceeb rau NMTFA, ua rau nws haum rau ntau yam kev siv tshuaj lom neeg. NMTFA feem ntau muaj nyob rau hauv cov khoom siv crystalline nrog lub ntsiab lus yaj ntawm kwv yees li 62 ° C thiab ua kom pom kev solubility zoo hauv cov kuab tshuaj polar xws li acetone thiab ethanol. Nws qhov kev ruaj khov nyob rau hauv ntau yam mob tso cai rau nws siv tau zoo hauv kev tshawb fawb hauv chaw kuaj mob thiab cov txheej txheem kev lag luam. Siv Organic Synthesis: NMTFA ua haujlwm ua ib qho tseem ceeb hauv kev tsim cov organic synthesis, tshwj xeeb tshaj yog hauv kev qhia txog trifluoromethyl pawg rau hauv cov organic molecules. Lub peev xwm no yog qhov tseem ceeb rau kev tsim cov tshuaj, agrochemicals, thiab cov tshuaj tshwj xeeb nrog kev ua haujlwm ntawm lub cev thiab kev ruaj khov tshuaj. Tshuaj Chemistry: Hauv kev siv tshuaj, NMTFA yog siv ua tus precursor hauv kev tsim cov khoom xyaw tshuaj (APIs) vim nws muaj peev xwm los muab cov khoom siv pharmacological xav tau. Nws ua lub luag haujlwm tseem ceeb hauv kev kho mob los ntawm kev ua kom muaj kev hloov pauv ntawm cov tshuaj molecules kom txhim kho kev ua haujlwm thiab txo qhov kev cuam tshuam ntawm cov metabolism. Cov Tshuaj Tshwj Xeeb: NMTFA pom daim ntawv thov hauv kev tsim cov tshuaj tshwj xeeb xws li surfactants, plasticizers, thiab cov intermediates nyuaj siv hauv kev tsim cov agrochemicals thiab cov tshuaj zoo. Nws qhov kev hloov pauv hauv kev hloov pauv tshuaj ua rau nws muaj txiaj ntsig zoo hauv cov qauv uas xav tau kev tswj hwm meej ntawm cov qauv molecular thiab kev ua haujlwm. Kev tsim N-Methyl-2,2,2-trifluoroacetamide yog tsim los ntawm kev sib xyaw ntawm trifluoroacetic acid nrog methylamine. Cov txheej txheem no cuam tshuam nrog kev sib xyaw ntawm trifluoroacetic acid nrog methylamine nyob rau hauv cov xwm txheej tswj hwm los tsim NMTFA. Cov tshuaj feem ntau ua tiav nyob rau hauv qhov muaj cov catalyst tsim nyog los pab txhawb kev tsim amide bond. Cov txheej txheem purification xws li recrystallization lossis chromatography yog siv los tau txais NMTFA hauv kev huv si siab tsim nyog rau kev siv hauv kev lag luam. Txoj kev yooj yim synthesis thiab muaj cov khoom siv raw pab rau nws cov nqi-zoo thiab kev siv dav hauv kev tshawb fawb kev kawm thiab cov txheej txheem kev lag luam. Hauv kev xaus lus, N-methyl-2,2,2-trifluoroacetamide yog ib qho tshuaj sib xyaw ua ke uas muaj ntau yam kev siv tseem ceeb hauv kev tsim cov organic, tshuaj lom neeg, thiab kev tsim cov tshuaj tshwj xeeb. Nws cov khoom siv tshuaj tshwj xeeb, suav nrog kev ruaj khov, kev ua haujlwm, thiab yooj yim ntawm kev tsim, pab txhawb rau nws qhov tseem ceeb hauv kev txhim kho cov thev naus laus zis thoob plaws ntau yam kev lag luam thiab kev tshawb fawb.