Mecillinam CAS: 32887-01-7

Mecillinam feem ntau siv rau hauv kev kho mob rau kev kho mob ntawm cov kab mob tso zis tsis yooj yim (UTIs) uas tshwm sim los ntawm cov kab mob Gram-negative uas yooj yim kis tau, tshwj xeeb tshaj yog Escherichia coli. Nws cov kev ua haujlwm nqaim tso cai rau kev kho mob tsom mus rau cov kab mob uropathogens thaum txo qis kev cuam tshuam rau cov kab mob ib txwm muaj. Mecillinam feem ntau nyiam rau UTIs vim nws cov txiaj ntsig zoo, kev nyab xeeb, thiab muaj peev xwm tsawg rau kev ua kom tsis kam. Ntxiv rau UTIs, mecillinam siv rau kev tswj hwm lwm yam kab mob hauv zos, xws li prostatitis thiab cov kab mob hauv txoj hlab pa qis, qhov twg cov kab mob Gram-negative uas yooj yim kis tau raug cuam tshuam. Nws cov haujlwm xaiv tawm tsam Enterobacteriaceae ua rau nws yog ib qho kev xaiv zoo hauv kev kho cov kab mob tshwj xeeb no thaum zam kev siv tshuaj tua kab mob dav dav tsis tsim nyog. Mecillinam cov tshuaj noj thiab cov khoom pharmacokinetic zoo ua rau nws yooj yim rau kev kho mob sab nraud ntawm cov kab mob me me mus rau nruab nrab, tso cai rau cov neeg mob kom ua tiav lawv txoj kev kho mob zoo. Nws cov txiaj ntsig zoo hauv kev tsom mus rau cov kab mob Gram-negative qhia txog nws qhov tseem ceeb hauv kev tswj hwm cov kab mob hauv zos. Ntxiv mus, mecillinam siv rau hauv qee cov kev kho mob tiv thaiv kom tiv thaiv cov kab mob UTI rov tshwm sim lossis ua kev tiv thaiv thaum phais mob uas cov kab mob Gram-negative ua rau muaj kev pheej hmoo ntawm kev kis kab mob. Nws lub peev xwm los ua kom muaj ntau cov ntaub so ntswg hauv cov zis thiab tawm tsam cov kab mob uropathogens ua rau nws yog tus neeg sawv cev tiv thaiv kab mob zoo hauv cov xwm txheej tshwj xeeb. Zuag qhia tag nrho, mecillinam ua haujlwm ua tus neeg sawv cev tiv thaiv kab mob zoo hauv kev kho mob ntawm cov kab mob hauv zos uas tshwm sim los ntawm cov kab mob Gram-negative uas yooj yim kis tau, muab cov kws kho mob txoj hauv kev kho mob uas tsom mus rau thiab ua tau zoo nrog kev pheej hmoo tsawg ntawm kev tiv thaiv. Nws qhov chaw me me ua tus neeg sawv cev nqaim-spectrum ua rau nws yog ib qho cuab yeej tseem ceeb hauv kev siv zog tiv thaiv kab mob, txhawb kev siv tshuaj tua kab mob kom zoo thiab txo qis kev tshwm sim ntawm cov kab mob tiv thaiv ntau yam tshuaj.