Linezolid CAS: 165800-03-3

Linezolid siv dav hauv kev kho mob rau kev tswj cov kab mob Gram-positive loj heev uas tiv taus lwm yam tshuaj tua kab mob. Nws feem ntau yog sau rau cov tawv nqaij thiab cov nqaij mos mos, mob ntsws, mob ntshav, thiab pob txha kis los ntawm MRSA, VRE, thiab lwm yam kab mob uas tiv taus ntau yam tshuaj. Linezolid lub peev xwm los tsom cov kab mob nyuaj kho no ua rau nws yog tus neeg sawv cev kho mob tseem ceeb hauv kev tawm tsam cov kab mob nyuaj. Hauv tsev kho mob, linezolid feem ntau siv rau kev kho mob ntawm cov kab mob hauv tsev kho mob thiab mob ntsws ntsig txog kev kho mob vim nws muaj ntau yam kev ua haujlwm thiab kev nyab xeeb zoo. Nws cov mis noj tso cai rau kev kho mob sab nraud yooj yim ntawm qee yam kab mob, muab kev kho mob zoo rau cov neeg mob tiv thaiv cov kab mob uas muaj teeb meem. Ntxiv mus, linezolid siv rau hauv kev kho mob ntsws thiab lwm yam kab mob mycobacterial ua ib feem ntawm kev kho mob ua ke. Nws cov txheej txheem tshwj xeeb ntawm kev ua haujlwm thiab kev nkag mus rau hauv cov ntaub so ntswg zoo ua rau nws yog qhov ntxiv rau cov cuab yeej siv rau kev kho mob ntsws uas tiv taus tshuaj thiab cov kab mob mycobacterial uas tsis yog ntsws. Hauv kev tshawb fawb, linezolid siv ua tus qauv siv hauv kev sim tshuaj tua kab mob kom ntsuas qhov rhiab heev ntawm cov kab mob bacterial rau cov tshuaj tua kab mob no. Los ntawm kev txiav txim siab qhov tsawg kawg nkaus inhibitory concentration (MIC) ntawm linezolid tawm tsam cov kab mob tshwj xeeb, cov kws tshawb fawb tuaj yeem coj cov tswv yim kho mob tsim nyog thiab saib xyuas cov qauv tiv thaiv. Zuag qhia tag nrho, linezolid ua lub luag haujlwm tseem ceeb hauv kev tswj hwm cov kab mob Gram-positive nyuaj, muab cov kws kho mob ib qho kev xaiv kho mob muaj zog thiab txhim khu kev qha tiv thaiv cov kab mob tiv thaiv tshuaj. Nws cov txiaj ntsig zoo, kev kam rau siab, thiab kev hloov pauv ua rau nws yog ib qho tseem ceeb hauv kev sib ntaus sib tua cov kab mob sib kis, tshwj xeeb tshaj yog cov uas tshwm sim los ntawm cov kab mob tiv thaiv ntau yam tshuaj.