Ibandronate Sodium CAS: 138844-81-2 Chaw Tsim Khoom Siv

Ibandronate sodium tau siv los kawm txog nws cov nyhuv rau kev loj hlob thiab ultrastructure ntawm Leishmania thiab Giardia los ntawm kev tsim cov kab sib sau ua ke. Nws kuj tau siv los piav qhia txoj kev uas cov bisphosphonates uas muaj nitrogen (N-BPs) nkag mus rau hauv cytosol thiab inhibit lawv lub hom phiaj molecular. Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM). Ibandronate sodium kuj yog ib qho tshuaj inhibitor resorption pob txha. Nws tau raug tshawb nrhiav rau hauv vitro anti-tumor teebmeem, xws li apoptosis induction, inhibitor ntawm cell loj hlob, inhibition ntawm invasive behavior, thiab inhibition ntawm angiogenesis thiab rau nws lub luag haujlwm hauv vivo hauv ntau yam mob qog noj ntshav suav nrog mob qog noj ntshav mis thiab prostate.