Ibandronate Sodium CAS: 138844-81-2 Chaw tsim tshuaj paus

Ibandronate sodium tau siv los kawm txog nws cov txiaj ntsig ntawm kev loj hlob thiab ultrastructure ntawm Leishmania thiab Giardia los ntawm tiam ntawm cov kev xav nkhaus.Nws kuj tau siv los qhia txog txoj hauv kev uas muaj nitrogen-muaj bisphosphonates (N-BPs) nkag mus rau cytosol thiab inhibit lawv lub hom phiaj molecular.Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM).Ibandronate sodium kuj yog cov pob txha resorption inhibitor.Nws tau raug tshawb xyuas rau hauv vitro los tiv thaiv qog, xws li apoptosis induction, inhibitor ntawm cell loj hlob, inhibition ntawm invasive cwj pwm, thiab inhibition ntawm angiogenesis thiab rau nws lub luag hauj lwm nyob rau hauv vivo nyob rau hauv ntau yam mob qog noj ntshav nrog rau lub mis thiab prostate cancer.