Fmoc-D-Cys(Trt)-OH CAS: 167015-11-4

Fmoc-D-Cys(Trt)-OH ua haujlwm ua lub cuab yeej tseem ceeb hauv kev tsim cov peptide, tshwj xeeb tshaj yog hauv kev tsim cov peptides uas muaj D-enantiomer ntawm cysteine ​​nrog kev ua kom raug. Pawg tiv thaiv Fmoc tiv thaiv pawg amino, ua kom muaj kev xaiv thaum lub sijhawm sib txuas peptide, thaum pawg trityl ntxiv ib txheej ntxiv ntawm kev tiv thaiv rau pawg thiol. Cov kws tshawb fawb siv Fmoc-D-Cys(Trt)-OH hauv kev tsim cov peptides rau ntau yam kev siv, suav nrog kev tsim cov tshuaj kho mob peptide, cov khoom siv biomaterials, thiab peptides nrog cov qauv tshwj xeeb. Nws qhov sib xws nrog cov txheej txheem tsim peptide txheem, hauv ob qho tib si theem khoom thiab theem kev daws teeb meem, txhim kho nws qhov kev hloov pauv hauv ntau yam kev tshawb fawb. Kev tshem tawm tswj hwm ntawm cov pab pawg tiv thaiv tso cai rau kev koom ua ke ntawm D-cysteine ​​rau hauv cov kab ke peptide, nthuav dav qhov ntau thiab tsawg ntawm cov peptides synthesizable. Ntxiv mus, Fmoc-D-Cys(Trt)-OH pom tias muaj txiaj ntsig zoo hauv kev tshawb fawb ntsig txog kev tsim kho protein, kev tsim cov khoom sib txuas disulfide, thiab cov tshuaj tiv thaiv peptide. Kev siv cov pab pawg tiv thaiv trityl ua rau muaj kev tswj hwm D-cysteine ​​reactivity kom raug, muab rau cov kws tshawb fawb ib lub cuab yeej muaj txiaj ntsig rau kev tsim cov peptides nrog kev hloov kho tshwj xeeb. Hauv kev xaus, Fmoc-D-Cys (Trt) -OH sawv cev rau ib qho cuab yeej siv tau ntau yam thiab tsis tseem ceeb hauv peptide chemistry, txhawb nqa cov kws tshawb fawb los tshawb nrhiav thiab hloov kho D-cysteine ​​reactivity rau ntau yam kev siv hauv kev tshawb fawb, tshwj xeeb tshaj yog tsom mus rau peptides uas muaj cov amino acid tseem ceeb no hauv D-configuration.