Fmoc-D-Asn(Trt)-OH CAS: 180570-71-2

Fmoc-D-Asn(Trt)-OH yog ib qho tseem ceeb hauv kev tsim cov peptide, tshwj xeeb tshaj yog hauv kev tsim cov peptides uas muaj D-enantiomer ntawm asparagine nrog kev ua kom raug. Pawg tiv thaiv Fmoc tiv thaiv cov amino pawg, ua kom muaj kev xaiv thaum lub sijhawm sib txuas peptide, thaum pawg trityl ntxiv ib txheej ntxiv ntawm kev tiv thaiv. Cov kws tshawb fawb siv Fmoc-D-Asn(Trt)-OH dav dav hauv kev tsim cov peptides rau ntau yam kev siv, suav nrog kev tsim tshuaj, biomaterials, thiab kev tsim cov bioactive peptides nrog cov qauv stereochemical tshwj xeeb. Nws qhov sib xws nrog cov txheej txheem tsim peptide txheem, hauv ob qho tib si solid-phase thiab cov tswv yim daws teeb meem, txhim kho nws qhov kev hloov pauv hauv ntau yam kev tshawb fawb. Kev tshem tawm tswj hwm ntawm cov pab pawg tiv thaiv tso cai rau kev koom ua ke ntawm D-asparagine rau hauv cov kab ke peptide, nthuav dav cov repertoire ntawm synthesizable peptides. Ntxiv mus, Fmoc-D-Asn(Trt)-OH pom tias muaj txiaj ntsig zoo hauv kev tsim cov peptides rau kev tshawb fawb proteomics thiab kawm txog cov txheej txheem cellular. Kev siv cov pab pawg tiv thaiv trityl ua rau muaj kev tswj hwm D-asparagine reactivity kom raug, muab rau cov kws tshawb fawb ib lub cuab yeej muaj txiaj ntsig rau kev tsim cov peptides nrog kev hloov kho tshwj xeeb. Hauv kev xaus, Fmoc-D-Asn (Trt) -OH sawv cev rau ib qho cuab yeej siv tau ntau yam thiab tsis tseem ceeb hauv peptide chemistry, txhawb nqa cov kws tshawb fawb los tshawb nrhiav thiab hloov kho D-asparagine reactivity rau ntau yam kev siv hauv kev tshawb fawb, tshwj xeeb tshaj yog tsom mus rau peptides uas muaj D-amino acids.