Fmoc-Cys(Tab sis)-OH CAS: 67436-13-9

Fmoc-Cys(But)-OH ua haujlwm ua lub cuab yeej tseem ceeb hauv kev tsim cov peptide, tshwj xeeb tshaj yog hauv kev tsim cov peptides uas muaj cysteine ​​nrog kev ua kom raug. Pawg tiv thaiv Fmoc tiv thaiv cov amino pawg, ua kom muaj kev xaiv thaum lub sijhawm sib txuas peptide, thaum pawg butyl ntxiv ib txheej ntxiv ntawm kev tiv thaiv rau pawg thiol. Cov kws tshawb fawb siv Fmoc-Cys(But)-OH ntau hauv kev tsim cov peptides rau ntau yam kev siv, suav nrog kev tsim cov tshuaj peptide, bioconjugation, thiab kev tsim cov peptides nrog cov yam ntxwv tshwj xeeb. Nws qhov sib xws nrog cov txheej txheem tsim peptide txheem, hauv ob qho tib si solid-phase thiab solution-phase strategy, txhim kho nws qhov kev ua tau zoo hauv ntau yam kev tshawb fawb. Kev tshem tawm tswj hwm ntawm cov pawg tiv thaiv tso cai rau kev koom ua ke ntawm cysteine ​​rau hauv cov kab ke peptide, nthuav dav ntau yam ntawm cov peptides synthesizable. Ntxiv mus, Fmoc-Cys(But)-OH pom tias muaj txiaj ntsig zoo hauv kev kawm txog kev sib sau ua ke ntawm cov protein, kev tsim cov disulfide bond, thiab kev tsim cov khoom siv peptide. Kev siv cov pab pawg tiv thaiv butyl ua rau muaj kev tswj hwm zoo ntawm cysteine ​​reactivity, muab cov kws tshawb fawb ib lub cuab yeej muaj txiaj ntsig rau kev tsim cov peptides nrog kev hloov kho tshwj xeeb. Hauv kev xaus, Fmoc-Cys (But) -OH sawv cev rau ib qho cuab yeej siv tau ntau yam thiab tsis tseem ceeb hauv peptide chemistry, txhawb nqa cov kws tshawb fawb los tshawb nrhiav thiab hloov kho cysteine ​​reactivity rau ntau yam kev siv hauv kev tshawb fawb, tshwj xeeb tshaj yog tsom mus rau peptides uas muaj cov amino acid tseem ceeb no.