Fmoc-Arg(pbf)-OH CAS:154445-77-9

Fmoc-Arg(pbf)-OH ua lub luag haujlwm tseem ceeb hauv kev tsim cov peptide, tshwj xeeb tshaj yog nyob rau hauv cov xwm txheej uas xav tau kev tswj hwm kev tiv thaiv ntawm guanidine nitrogen hauv arginine. Pawg tiv thaiv Fmoc tiv thaiv pawg amino, pab txhawb kev xaiv cov tshuaj tiv thaiv thaum lub sijhawm peptide coupling, thaum pawg pbf ntawm guanidine nitrogen muab ib txheej ntxiv ntawm kev tiv thaiv. Cov kws tshawb fawb siv Fmoc-Arg(pbf)-OH rau kev tsim cov peptides nrog kev hloov kho guanidine tshwj xeeb, cuam tshuam rau lawv cov haujlwm biological. Txoj kev tiv thaiv ob npaug ua rau muaj kev tswj hwm meej ntawm guanidine reactivity, ua rau cov tshuaj no muaj txiaj ntsig zoo hauv kev tsim thiab kev txhim kho cov peptides rau kev tshawb fawb txog kev tiv thaiv kab mob, bioconjugation, thiab tshuaj lom neeg. Kev sib raug zoo ntawm Fmoc-Arg(pbf)-OH nrog cov txheej txheem peptide synthesis txheem, suav nrog cov khoom siv peptide synthesis (SPPS), txhim kho nws cov txiaj ntsig. Cov tshuaj no pom daim ntawv thov hauv kev tsim cov peptides rau kev sim tshuaj lom neeg, kev tshawb pom tshuaj, thiab kev txhim kho cov ntaub ntawv raws li peptide. Kev tshem tawm cov pab pawg tiv thaiv uas tswj tau tso cai rau kev koom ua ke ntawm arginine nrog guanidine hloov kho, pab txhawb rau ntau yam peptides uas tuaj yeem tsim tau. Hauv kev xaus, Fmoc-Arg (pbf) -OH sawv cev rau ib qho cuab yeej tshwj xeeb thiab siv tau ntau yam hauv peptide chemistry, txhawb nqa cov kws tshawb fawb los tshawb nrhiav thiab hloov kho guanidine reactivity rau ntau yam kev siv hauv kev tshawb fawb thiab kev kho mob.