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Ofloxacin CAS: 82419-36-1
Ofloxacin yog ib hom tshuaj tua kab mob fluoroquinolone uas muaj zog tua kab mob ntau yam kab mob gram-negative thiab gram-positive. Nws tiv thaiv cov kab mob DNA gyrase thiab topoisomerase IV enzymes, cuam tshuam kev tsim cov DNA thiab ua rau cov kab mob tuag. Muaj nyob rau hauv kev noj, kev siv tshuaj pleev, thiab kev txhaj tshuaj rau hauv cov hlab ntsha, ofloxacin feem ntau yog siv rau kev kho mob ntau yam kab mob, suav nrog kev kis kab mob ntawm txoj hlab pa, kev kis kab mob ntawm txoj hlab zis, kev kis kab mob ntawm daim tawv nqaij thiab cov nqaij mos, thiab cov kab mob sib kis los ntawm kev sib deev. Nws muaj ntau yam kev ua haujlwm, kev siv tshuaj zoo, thiab kev ua haujlwm zoo ua rau ofloxacin yog ib qho kev xaiv kho mob zoo hauv zej zog thiab hauv tsev kho mob.
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Norfloxacin CAS: 70458-96-7
Norfloxacin yog ib hom tshuaj tua kab mob fluoroquinolone uas muaj zog tiv thaiv kab mob dav dav tawm tsam cov kab mob gram-negative thiab qee cov kab mob gram-positive. Nws tiv thaiv cov kab mob DNA gyrase thiab topoisomerase IV, cov enzymes tseem ceeb uas koom nrog kev tsim thiab kho DNA, yog li ua rau muaj cov teebmeem tua kab mob. Norfloxacin muaj nyob rau hauv cov tshuaj noj, suav nrog cov ntsiav tshuaj thiab cov tshuaj ncua, rau kev kho ntau yam kab mob bacterial, xws li kab mob urinary, kab mob gastrointestinal, kab mob ua pa, thiab kab mob sib kis los ntawm kev sib deev. Nws feem ntau raug sau tseg vim nws cov txiaj ntsig zoo, kev kam rau siab, thiab kev noj tshuaj yooj yim.
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Nisin CAS: 1414-45-5
Nisin yog ib hom peptide tua kab mob ntuj tsim los ntawm qee hom kab mob Lactococcus lactis. Nws yog ib hom lantibiotics, uas muaj cov qauv tshwj xeeb uas muaj lanthionine thiab methyllanthionine amino acids. Nisin muaj zog tua kab mob tiv thaiv ntau yam kab mob gram-positive, suav nrog cov kab mob hauv zaub mov xws li Listeria monocytogenes thiab Staphylococcus aureus. Vim nws qhov kub thiab txias thiab sib haum nrog ntau yam kev ua zaub mov, nisin siv dav ua ib yam khoom tiv thaiv ntuj hauv kev lag luam zaub mov kom tiv thaiv kev loj hlob ntawm cov kab mob thiab ua kom cov khoom noj khoom haus ntev dua.
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Oxytetracycline dihydrate CAS: 6153-64-6
Oxytetracycline dihydrate yog ib hom tshuaj oxytetracycline, uas yog ib hom tshuaj tua kab mob dav dav uas yog ib feem ntawm pawg tetracycline. Ib yam li lwm cov tshuaj tetracyclines, nws tiv thaiv cov protein tsim los ntawm kev khi rau 30S ribosomal subunit, yog li ua rau muaj cov teebmeem bacteriostatic tiv thaiv ntau yam kab mob gram-positive thiab gram-negative. Oxytetracycline dihydrate zoo ib yam li oxytetracycline tab sis muaj ob lub molecule dej hauv nws cov qauv siv lead ua. Nws muaj nyob rau hauv ntau hom tshuaj rau tib neeg thiab tsiaj txhu siv.
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Ornidazole CAS: 16773-42-5
Ornidazole yog ib hom tshuaj tua kab mob nitroimidazole thiab tshuaj tua kab mob protozoal uas muaj zog dav dav tiv thaiv cov kab mob anaerobic thiab protozoa. Nws ua haujlwm los ntawm kev ua puas rau DNA ntawm cov kab mob me me, ua rau lawv tuag. Ornidazole muaj nyob rau hauv cov tshuaj noj, suav nrog cov ntsiav tshuaj thiab cov tshuaj sib xyaw, rau kev kho mob ntawm ntau yam kab mob, xws li kab mob vaginosis, trichomoniasis, giardiasis, thiab amoebiasis. Nws feem ntau raug sau tseg vim nws cov txiaj ntsig zoo, kev kam rau siab, thiab kev noj tshuaj yooj yim.
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Oxacillin sodium ntsev monohydrate CAS: 7240-38-2
Oxacillin sodium ntsev monohydrate yog ib hom tshuaj tua kab mob beta-lactam uas muaj qhov nqaim, zoo ib yam li oxacillin sodium ntsev, nrog rau ib lub molecule dej ntxiv rau hauv nws cov qauv siv lead ua. Nws zoo li methicillin thiab nafcillin, nws ua haujlwm zoo tiv thaiv penicillinase-producing staphylococci. Oxacillin sodium ntsev monohydrate tiv thaiv cov kab mob cell phab ntsa los ntawm kev cuam tshuam nrog peptidoglycan cross-linking, ua rau muaj cov kab mob bactericidal tawm tsam cov kab mob uas yooj yim kis tau. Muaj nyob rau hauv cov tshuaj txhaj rau kev txhaj tshuaj lossis intramuscular, nws feem ntau siv rau hauv cov chaw kho mob rau kev kho cov kab mob uas tshwm sim los ntawm penicillinase-producing Staphylococcus aureus hom.
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Pefloxacin mesylate CAS: 70458-95-6
Pefloxacin mesylate yog ib hom tshuaj tua kab mob fluoroquinolone uas muaj zog tua kab mob dav dav tiv thaiv cov kab mob gram-positive thiab gram-negative. Nws ua haujlwm los ntawm kev txwv tsis pub cov kab mob DNA tsim los ntawm kev sib cuam tshuam nrog cov enzymes xws li DNA gyrase thiab topoisomerase IV, ua rau muaj kev cuam tshuam rau cov kab mob. Pefloxacin mesylate muaj nyob rau hauv ntau hom tshuaj rau kev noj thiab kev txhaj tshuaj, muab cov kev xaiv kho mob zoo rau ntau yam kab mob bacterial.
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Novobiocin sodium ntsev CAS: 1476-53-5
Novobiocin sodium ntsev yog ib yam tshuaj tua kab mob uas muaj los ntawm cov kab mob me me uas yog los ntawm tsev neeg coumarin, uas tau rho tawm los ntawm cov kab mob Streptomyces. Nws muaj cov haujlwm tua kab mob dav dav, tshwj xeeb tshaj yog tiv thaiv cov kab mob gram-positive, los ntawm kev txwv DNA gyrase, ib qho enzyme tseem ceeb uas koom nrog kev rov ua dua thiab kev sau ntawv ntawm DNA. Novobiocin feem ntau siv hauv cov chaw kuaj mob microbiology rau nws txoj kev xaiv txwv Staphylococcus aureus thiab lwm yam coagulase-positive staphylococci, ua rau nws yog ib qho cuab yeej muaj txiaj ntsig zoo rau kev txheeb xyuas cov kab mob thiab kev kuaj mob antimicrobial.
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Nitrocefin CAS: 41906-86-9
Nitrocefin yog ib qho chromogenic cephalosporin substrate siv rau hauv microbiology rau kev kuaj pom beta-lactamase ua haujlwm hauv cov kab mob. Nws ua haujlwm ua ib qho cuab yeej kuaj mob los txheeb xyuas cov kab mob uas tsim cov beta-lactamase enzymes uas muaj peev xwm hydrolyzing beta-lactam tshuaj tua kab mob, xws li penicillins thiab cephalosporins. Nitrocefin hloov xim ntawm daj mus rau liab thaum muaj beta-lactamase, ua rau pom sai sai ntawm cov enzyme ua haujlwm. Cov khoom no ua rau nitrocefin yog ib qho cuab yeej muaj txiaj ntsig hauv cov chaw kuaj mob rau kev tshuaj ntsuam cov kab mob thiab coj kev txiav txim siab kho tshuaj tua kab mob.
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Oleandomycin phosphate CAS: 7060-74-4
Oleandomycin phosphate yog ib hom tshuaj tua kab mob macrolide uas tau los ntawm Streptomyces antibioticus, uas paub txog nws cov kev ua haujlwm tiv thaiv kab mob dav dav tiv thaiv cov kab mob gram-positive. Nws tiv thaiv cov protein tsim los ntawm cov kab mob los ntawm kev khi rau 50S ribosomal subunit, ua rau muaj cov teebmeem bacteriostatic. Oleandomycin phosphate feem ntau siv rau hauv kev kho tsiaj rau kev kho cov kab mob bacterial hauv cov tsiaj txhu thiab nqaij qaib. Nws muaj nyob rau hauv cov qauv tsim nyog rau kev noj los daws cov kab mob ua pa, kab mob plab hnyuv, thiab lwm yam kab mob bacterial uas cuam tshuam rau cov tsiaj txhu.
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Natamycin (Pimaricin) CAS: 7681-93-8
Natamycin, tseem hu ua pimaricin, yog ib yam tshuaj tua kab mob uas tshwm sim los ntawm cov kab mob Streptomyces natalensis. Nws siv dav ua cov tshuaj khaws cia zaub mov kom tiv thaiv kev loj hlob ntawm pwm thiab poov xab hauv ntau yam khoom noj mis nyuj, nqaij, thiab cov khoom ci. Natamycin muaj txiaj ntsig zoo rau ntau hom fungi, suav nrog Aspergillus, Penicillium, thiab Fusarium, thaum tseem muaj kev nyab xeeb rau tib neeg noj. Cov khoom no tau lees paub rau nws qhov ruaj khov, tiv taus cua sov, thiab muaj kev cuam tshuam tsawg kawg nkaus rau cov khoom noj khoom haus, ua rau nws yog qhov kev xaiv zoo hauv kev tsim khoom noj thiab kev khaws cia.
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Nadifloxacin CAS: 124858-35-1
Nadifloxacin yog ib hom tshuaj tua kab mob fluoroquinolone uas siv rau sab nraud los kho ntau yam kab mob ntawm daim tawv nqaij. Nws muaj zog tua ntau yam kab mob, tshwj xeeb tshaj yog cov uas muaj teeb meem ntawm daim tawv nqaij thiab mob dermatitis. Nadifloxacin ua haujlwm los ntawm kev txwv tsis pub cov kab mob DNA rov tsim dua, yog li ntawd thiaj li tua tau cov kab mob phem ntawm daim tawv nqaij. Cov khoom no muaj nyob rau hauv daim ntawv ntawm cov tshuaj pleev, cov gels, lossis cov tshuaj pleev rau sab nraud. Nws tau txais kev pom zoo thiab feem ntau cov kws kho mob tau sau ntawv rau nws vim nws muaj txiaj ntsig zoo thiab muaj kev nyab xeeb hauv cov mob dermatological.
