-
Pristinamycin CAS: 270076-60-3
Pristinamycin yog ib hom tshuaj tua kab mob sib xyaw ua ke uas muaj ob yam khoom xyaw nquag, pristinamycin I thiab pristinamycin II. Nws yog ib feem ntawm pawg tshuaj tua kab mob streptogramin thiab muaj cov haujlwm bacteriostatic thiab bactericidal tawm tsam ntau yam kab mob gram-positive, suav nrog Staphylococcus aureus thiab Streptococcus pneumoniae. Pristinamycin ua haujlwm los ntawm kev txwv tsis pub cov protein tsim tawm ntawm cov kab mob, ua rau nws zoo rau kev kho cov kab mob ntawm daim tawv nqaij thiab cov nqaij mos, cov kab mob ntawm txoj hlab pa, thiab lwm yam kab mob ntawm cov kab mob uas tshwm sim los ntawm cov kab mob uas yooj yim kis tau.
-
Ribostamycin sulfate CAS: 53797-35-6
Ribostamycin sulfate yog ib hom tshuaj tua kab mob aminoglycoside uas tau los ntawm Streptomyces griseoluteus. Nws muaj zog tua cov kab mob ntau yam gram-negative thiab qee cov kab mob gram-positive los ntawm kev txwv tsis pub cov protein tsim tawm. Ribostamycin sulfate feem ntau siv rau kev kho ntau yam kab mob, suav nrog cov kab mob ntawm txoj hlab zis, cov kab mob ntawm txoj hlab pa, cov kab mob ntawm daim tawv nqaij thiab cov nqaij mos, thiab septicemia uas tshwm sim los ntawm cov kab mob uas yooj yim kis tau.
-
Rifampicin CAS: 13292-46-1
Rifampicin, tseem hu ua rifampin, yog ib hom tshuaj tua kab mob uas muaj ntau yam kev siv. Nws siv dav hauv kev kho mob ntsws, mob ruas, thiab lwm yam kab mob bacterial. Rifampicin ua haujlwm los ntawm kev txwv tsis pub RNA synthesis hauv cov kab mob, ua rau lawv tsis muaj peev xwm rov ua dua thiab muaj sia nyob. Vim nws muaj zog tiv thaiv kab mob thiab ua haujlwm zoo rau cov kab mob mycobacterial, rifampicin yog ib qho tseem ceeb ntawm kev kho mob ua ke rau mob ntsws thiab lwm yam kab mob sib kis.
-
Puromycin dihydrochloride CAS: 58-58-2
Puromycin dihydrochloride yog ib yam tshuaj tua kab mob thiab tshuaj uas ua rau cov protein synthesis inhibitor muaj zog uas tau los ntawm Streptomyces alboniger. Nws feem ntau siv rau hauv kev tshawb fawb txog molecular biology los xaiv cov protein synthesis hauv cov cell los ntawm kev ua kom tsis txhob muaj kev txhais lus thaum lub sijhawm synthesis protein. Puromycin dihydrochloride raug muab tso rau hauv cov saw peptide tshiab, ua rau cov polypeptides tsis tiav thiab thaum kawg tuag. Vim nws txoj kev ua haujlwm tshwj xeeb, puromycin dihydrochloride yog ib qho cuab yeej muaj txiaj ntsig zoo rau kev kawm txog kev tsim cov protein, kev ua haujlwm ntawm ribosome, kev qhia txog gene, thiab kev muaj sia nyob ntawm cell hauv kev sim.
-
Protionamide CAS: 14222-60-7
Protionamide yog ib hom tshuaj tua kab mob uas yog ib feem ntawm pawg thioamide, feem ntau yog siv rau kev kho mob ntsws uas tiv taus ntau yam tshuaj. Nws ua haujlwm los ntawm kev txwv tsis pub cov mycolic acid tsim nyob rau hauv phab ntsa ntawm cov kab mob, ua rau Mycobacterium tuberculosis puas tsuaj. Protionamide feem ntau raug sau ua ke nrog lwm cov tshuaj tiv thaiv ntsws ua ib feem ntawm kev kho mob dav dav rau cov kab mob ntsws uas tiv taus tshuaj.
-
Potassium clavulanate CAS: 61177-45-5
Potassium clavulanate yog ib qho β-lactamase inhibitor uas feem ntau siv ua ke nrog qee yam tshuaj tua kab mob kom ua rau lawv muaj txiaj ntsig zoo tiv thaiv kab mob bacterial. Nws ua haujlwm los ntawm kev tiv thaiv kev puas tsuaj ntawm cov tshuaj tua kab mob los ntawm cov enzymes bacterial, yog li nthuav dav ntawm kev ua haujlwm thiab txhim kho cov txiaj ntsig kev kho mob. Potassium clavulanate feem ntau siv ua ke nrog cov tshuaj tua kab mob xws li amoxicillin los kho ntau yam kab mob bacterial.
-
Retapamulin CAS: 224452-66-8
Retapamulin yog ib hom tshuaj tua kab mob uas yog ib hom tshuaj pleuromutilin. Nws yog siv los kho cov kab mob ntawm daim tawv nqaij, tshwj xeeb yog cov kab mob impetigo uas tshwm sim los ntawm cov kab mob Staphylococcus aureus thiab Streptococcus pyogenes uas yooj yim kis tau. Retapamulin ua haujlwm los ntawm kev txwv tsis pub cov protein tsim los ntawm cov kab mob, ua rau cov kab mob kis tau ploj mus thiab kev kis kab mob ntawm daim tawv nqaij ploj mus.
-
Staurosporine, streptomyces staurosporeus CAS: 62996-74-1
Staurosporine yog ib yam khoom ntuj tsim los ntawm cov kab mob Streptomyces staurosporeus. Nws yog ib qho alkaloid muaj zog nrog kev ua haujlwm tseem ceeb ntawm lub cev, tshwj xeeb tshaj yog hauv kev tiv thaiv cov protein kinases thiab inducing cell apoptosis. Staurosporine tau raug kawm ntau yam rau nws cov khoom pharmacological, suav nrog nws cov peev xwm tiv thaiv kab mob qog noj ntshav thiab nws lub luag haujlwm ua ib qho cuab yeej tshawb fawb hauv kev tshawb fawb txog cell signaling.
-
Phosphomycin disodium ntsev CAS: 26016-99-9
Phosphomycin disodium ntsev yog tshuaj tua kab mob dav dav uas siv rau kev kho mob ntawm ntau yam kab mob bacterial. Nws yog ib hom phosphonic acids thiab ua haujlwm los ntawm kev txwv tsis pub cov cell phab ntsa tsim cov kab mob. Cov hmoov dawb crystalline no yaj tau zoo heev hauv dej thiab feem ntau yog muab rau hauv cov hlab ntsha lossis noj. Phosphomycin disodium ntsev paub txog nws cov txiaj ntsig zoo tiv thaiv ntau yam kab mob gram-positive thiab gram-negative, ua rau nws yog ib qho kev xaiv ntau yam rau kev kho mob.
-
Phleomycin CAS: 11006-33-0
Phleomycin yog ib yam tshuaj tua kab mob muaj zog uas siv rau hauv kev tshawb fawb txog molecular biology rau kev xaiv cov cell uas muaj ib qho gene uas xav tau. Nrog rau lub mechanism ntawm kev ua haujlwm uas cuam tshuam nrog DNA cleavage, Phleomycin muaj txiaj ntsig zoo rau ntau yam kab mob thiab tau siv dav hauv ntau yam kev tshawb fawb. Cov tshuaj tua kab mob no feem ntau siv ua ke nrog lwm cov cim xaiv los tsim cov kab cell ruaj khov nrog kev hloov pauv genetic xav tau. Phleomycin muaj nyob rau hauv ob qho tib si kua thiab hmoov, ua rau nws siv tau ntau yam thiab yooj yim rau ntau yam kev teeb tsa kev sim. Cov kws tshawb fawb txaus siab rau nws qhov ua tau zoo thiab kev ntseeg siab hauv kev xaiv cov cell hloov pauv, ua rau nws yog ib qho cuab yeej muaj txiaj ntsig zoo hauv kev tshawb fawb txog genetic engineering.
-
Penicillin V potassium ntsev CAS: 132-98-9
Penicillin V potassium ntsev yog tshuaj tua kab mob uas siv los kho cov kab mob bacterial. Nws muaj penicillin V, uas yog potassium ntsev ntawm phenoxymethylpenicillin. Penicillin V ua haujlwm los ntawm kev cuam tshuam rau kev tsim cov peptidoglycan hauv phab ntsa cell ntawm cov kab mob bacterial. Qhov no ua rau phab ntsa cell ntawm cov kab mob bacterial tsis muaj zog thiab tua lossis tiv thaiv kev loj hlob ntawm cov kab mob uas yooj yim kis tau. Nws muaj nyob rau hauv cov ntsiav tshuaj lossis cov tshuaj uas noj rau kev kho mob sab nraud ntawm cov kab mob me me mus rau nruab nrab.
-
Penicillin G sodium ntsev (Benzylpenicillin sodium ntsev) CAS: 69-57-8
Penicillin G sodium ntsev yog ib hom tshuaj tua kab mob uas muaj penicillin G nyob rau hauv nws daim ntawv sodium ntsev. Nws ua haujlwm los ntawm kev txwv tsis pub cov txheej peptidoglycan hauv cov phab ntsa cell ntawm cov kab mob, tua cov kab mob uas yooj yim kis tau. Penicillin G sodium ntsev muaj nyob rau hauv cov xim dawb lossis yuav luag dawb siv lead ua los yog hmoov uas yuav tsum tau rov ua dua rau hauv cov kua ua ntej txhaj tshuaj. Nws muab kev xa mus rau txhua lub cev ntawm penicillin G los kho cov kab mob bacterial.
