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1 '1-Bis(diphenylphosphino)ferrocene Palladium(II)chloride dichloromethane chloride CAS:95464-05-4
1,1-Bis(diphenylphosphino)ferrocene Palladium(II) Chloride Dichloromethane Complex, nrog rau cov mis tshuaj [Pd(dppf)Cl₂·CH₂Cl₂], yog ib qho organometallic compound uas muaj palladium(II) sib koom ua ke nrog dppf ligand thiab chlorides hauv cov tshuaj dichloromethane. Nws feem ntau siv rau hauv cov organic synthesis thiab catalysis.
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N-(6-bromopyridin-2-yl)thiourea CAS:439578-83-3
N-(6-Bromopyridin-2-yl)thiourea yog ib hom tshuaj uas muaj ib pawg thiourea txuas nrog rau 6-bromopyridin-2-yl moiety. Cov tshuaj no tau txais kev txaus siab rau kev siv tshuaj vim nws muaj ntau yam kev ua haujlwm pharmacological thiab kev siv kho mob. Nws cov yam ntxwv tshwj xeeb muab txoj hauv kev rau kev tsim cov tshuaj tshiab nrog cov hom phiaj tshwj xeeb, ua rau nws yog ib qho khoom muaj nqis hauv kev tshawb nrhiav thiab kev txhim kho tshuaj.
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2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL CAS: 269409-97-4
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, feem ntau hu ua TMDBP, yog ib qho tshuaj lom neeg uas yog ib feem ntawm cov phenolic boronic esters. Nws cov qauv molecular muaj ib pawg phenolic hydroxyl txuas rau ib lub nplhaib phenyl uas muaj ib qho cyclic ester moiety uas muaj boron. Cov tshuaj no muaj lub ntsiab lus tseem ceeb hauv kev tsim cov organic, tshwj xeeb tshaj yog hauv Suzuki-Miyaura cross-coupling reactions, qhov twg nws ua haujlwm ua ib qho boronic ester reagent muaj nqis. Tsis tas li ntawd, nws cov qauv cyclic boronate ruaj khov thiab qhov xwm txheej uas tsis ua rau mob ua rau nws muaj txiaj ntsig zoo hauv kev tsim cov ligands rau cov tshuaj hloov pauv hlau-catalyzed thiab hauv kev tsim cov ntaub ntawv ua haujlwm.
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1-Methyl-4-pyrazole boronic acid pinacol ester CAS: 761446-44-0
1-Methyl-4-pyrazole boronic acid pinacol ester yog ib qho tshuaj lom neeg uas tau muab faib ua boronic ester. Nws cov qauv molecular muaj cov boronic acid moiety txuas nrog lub nplhaib pyrazole hloov nrog pawg pinacol ester (-OC (CH₃)₂C (CH₃)₂O-). Cov tshuaj no muaj qhov tseem ceeb hauv kev tsim cov organic, tshwj xeeb tshaj yog hauv Suzuki-Miyaura cross-coupling reactions, qhov twg nws ua haujlwm ua cov tshuaj boronic ester reagent ntau yam. Tsis tas li ntawd, nws qhov kev ruaj khov, kev xaiv reactivity, thiab kev sib raug zoo nrog ntau yam kev mob ua rau nws muaj txiaj ntsig zoo hauv kev tsim cov tshuaj intermediates, agrochemicals, thiab cov ntaub ntawv ua haujlwm.
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Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS: 1784081-72-6
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- yog ib qho tshuaj sib xyaw ua ke nrog lub cyclopenta[b]pyrrole core qauv thiab ib sab hexahydro-1H-pyrrole-3a(1H)-methanol. Cov molecule no tseem ceeb hauv kev kho mob vim nws cov haujlwm pharmacological. Nws cov qauv tshwj xeeb muab cov cib fim rau kev txhim kho cov tshuaj tshiab, tshwj xeeb tshaj yog tsom mus rau cov kab mob neurological thiab lwm yam kab mob uas kev hloov pauv ntawm cov neurotransmitter receptors thiab transporters yog qhov tseem ceeb. Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- ua haujlwm ua lub scaffold rau cov kws tshuaj kho mob tshawb nrhiav cov neeg sawv cev kho mob tshiab nrog cov khoom pharmacokinetic zoo tshaj plaws thiab txo cov kev phiv.
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trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid CAS:169248-97-9
Trans-1-(tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid yog ib qho molecule complex uas muaj ib lub nplhaib pyrrolidine hloov nrog ib pawg tert-butoxycarbonyl ntawm qhov chaw 1 thiab ib pawg 3-(trifluoromethyl)phenyl ntawm qhov chaw 4. Cov tshuaj no muaj lub ntsiab lus tseem ceeb hauv kev kho mob tshuaj, feem ntau yog vim nws muaj peev xwm ua ib qho pharmacophore hauv kev tsim tshuaj. Nws cov qauv nyuaj muab cov sijhawm rau kev tsim cov neeg sawv cev kho mob tshiab nrog cov khoom pharmacological tshwj xeeb, tshwj xeeb tshaj yog tsom mus rau txoj hauv kev uas cuam tshuam nrog cov kab mob o, mob qog noj ntshav, lossis cov kab mob hauv lub paj hlwb.
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(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS: 1262849-90-0
(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride yog ib qho tshuaj lom neeg uas muaj lub nplhaib pyrrolidine hloov nrog ib pawg ethyl ntawm 3-txoj haujlwm thiab ib pawg tert-butyl ntawm 1-txoj haujlwm. Cov tshuaj no tau nyiam kev saib xyuas hauv kev kho mob vim nws cov qauv stereochemical thiab cov ntawv thov pharmacological. Nws qhov kev npaj tshwj xeeb muab txoj hauv kev rau kev tsim cov neeg sib tw tshuaj tshiab nrog cov hom phiaj tshwj xeeb, ua rau nws yog ib qho khoom muaj nqis hauv kev tshawb pom tshuaj thiab kev txhim kho.
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Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS: 1233501-65-9
Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride yog ib qho tshuaj sib xyaw ua ke uas muaj lub nplhaib pyrrolidine hloov nrog pawg ethyl ntawm 3-txoj haujlwm thiab pawg tert-butyl ntawm 1-txoj haujlwm. Cov tshuaj no tau txais kev saib xyuas hauv kev kho mob vim nws qhov nyuaj ntawm cov qauv thiab cov ntawv thov pharmacological. Nws qhov kev teeb tsa tshwj xeeb muab cov cib fim rau kev tsim cov tshuaj tshiab nrog cov hom phiaj tshwj xeeb, ua rau nws yog ib qho khoom muaj nqis hauv kev tshawb nrhiav tshuaj thiab kev txhim kho.
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4-Hydroxyphenylboronic acid pinacol ester CAS: 269409-70-3
4-Hydroxyphenylboronic acid pinacol ester, tseem hu ua 4-HPBA pinacol ester, yog ib qho tshuaj lom neeg uas poob rau hauv qeb ntawm boronic esters. Nws cov qauv molecular muaj ib qho boronic acid moiety txuas rau lub nplhaib phenyl hloov nrog ib pawg pinacol ester (-OC (CH₃)₂C (CH₃)₂O-). Cov tshuaj no muaj qhov tseem ceeb hauv kev tsim cov organic, tshwj xeeb tshaj yog hauv Suzuki-Miyaura cross-coupling reactions, qhov twg nws ua haujlwm ua ib qho boronic ester reagent ntau yam. Tsis tas li ntawd, nws qhov ruaj khov, yooj yim ntawm kev tuav, thiab kev sib raug zoo nrog ntau yam kev mob ua rau nws muaj txiaj ntsig zoo hauv kev tsim cov tshuaj intermediates, cov khoom ntuj, thiab cov ntaub ntawv ua haujlwm.
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Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS: 1057260-89-5
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride yog ib qho tshuaj lom neeg uas muaj cov pab pawg carbamate functional uas txuas rau lub nplhaib piperidine uas hloov nrog pab pawg benzyl ntawm lub nitrogen atom thiab pab pawg propyl ntawm lub carbon atom. Cov tshuaj no tau ua rau muaj kev txaus siab rau kev siv tshuaj vim nws qhov nyuaj ntawm cov qauv thiab cov ntawv thov pharmacological. Nws qhov kev npaj tshwj xeeb muab cov sijhawm rau kev tsim cov tshuaj tshiab nrog cov hom phiaj tshwj xeeb, ua rau nws yog ib qho khoom muaj nqis hauv kev tshawb nrhiav tshuaj thiab kev tsim kho.
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9,9-Dimethyl-9H-fluoren-2-yl-boronic acid CAS: 333432-28-3
9,9-Dimethyl-9H-fluoren-2-yl-boronic acid, feem ntau hu ua DMFBA, yog ib qho tshuaj lom neeg uas yog ib feem ntawm cov boronic acids. Nws cov qauv molecular muaj ib qho boronic acid moiety txuas nrog ib qho fluorene scaffold hloov nrog ob pawg methyl ntawm 9-txoj haujlwm. Cov tshuaj no muaj qhov tseem ceeb hauv kev tsim cov organic, tshwj xeeb tshaj yog hauv Suzuki-Miyaura cross-coupling reactions, qhov twg nws ua haujlwm ua ib qho versatile boronic acid reagent. Tsis tas li ntawd, nws cov qauv rigid thiab sterically hindered ua rau nws muaj txiaj ntsig zoo hauv ligand tsim rau kev hloov pauv hlau-catalyzed reactions thiab hauv kev tsim cov ntaub ntawv ua haujlwm.
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4-Carboxyphenylboronic acid CAS: 14047-29-1
4-Carboxyphenylboronic acid, tseem hu ua 4-Carboxyphenylboronic acid lossis 4-CPBA, yog ib qho tshuaj lom neeg uas yog ib feem ntawm cov boronic acids. Nws yog tus cwj pwm los ntawm nws cov boronic acid functional group (-B(OH)₂) txuas rau lub nplhaib phenyl hloov nrog pawg carboxylic acid (-COOH) ntawm qhov chaw para. Cov tshuaj no pom muaj ntau daim ntawv thov hauv kev tsim cov organic, tshwj xeeb tshaj yog hauv Suzuki-Miyaura cross-coupling reactions los tsim cov carbon-carbon bonds. Tsis tas li ntawd, nws lub peev xwm los khi rau diols thiab qab zib tau ua rau nws siv hauv kev tsim cov sensors rau kev saib xyuas glucose thiab hauv kev kho mob rau kev tsim cov enzyme inhibitors thiab receptor ligands.
