ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE CAS: 344-00-3

N-Ethyl 2-methyl-4,4,4-trifluoroacetoacetate (EMTFA) yog tus cwj pwm los ntawm nws cov qauv molecular, uas suav nrog trifluoromethyl pawg (-CF3) txuas nrog β-keto ester backbone. Cov qauv no muab kev ruaj khov thiab kev ua haujlwm tseem ceeb rau EMTFA, ua rau nws haum rau ntau yam kev siv tshuaj lom neeg. EMTFA feem ntau muaj nyob rau hauv cov kua ntshiab, tsis muaj xim nrog lub ntsiab lus kub ib puag ncig 140 ° C thiab qhia tau tias solubility zoo hauv cov kuab tshuaj organic xws li acetone thiab ethyl acetate. Nws qhov kev ruaj khov nyob rau hauv ntau yam mob tso cai rau nws siv tau zoo hauv kev tshawb fawb hauv chaw kuaj mob thiab cov txheej txheem kev lag luam. Siv Organic Synthesis: EMTFA ua haujlwm ua lub hauv paus tseem ceeb hauv kev tsim cov organic synthesis, tshwj xeeb tshaj yog hauv kev qhia txog trifluoromethylated motifs rau hauv cov organic molecules. Lub peev xwm no yog qhov tseem ceeb rau kev tsim cov tshuaj, agrochemicals, thiab cov tshuaj tshwj xeeb nrog kev ua haujlwm ntawm lub cev thiab kev ruaj khov tshuaj. Pharmaceutical Chemistry: Hauv kev siv tshuaj, EMTFA yog siv ua tus precursor hauv kev tsim cov khoom xyaw tshuaj nquag (APIs) vim nws muaj peev xwm los muab cov khoom pharmacological xav tau. Nws ua lub luag haujlwm tseem ceeb hauv kev kho mob los ntawm kev ua kom muaj kev hloov pauv ntawm cov tshuaj molecules kom txhim kho kev ua haujlwm thiab txo qhov kev cuam tshuam ntawm cov metabolism. Cov Tshuaj Tshwj Xeeb: EMTFA pom daim ntawv thov hauv kev tsim cov tshuaj tshwj xeeb xws li cov tshuaj tua kab, cov tshuaj tua kab, thiab cov tshuaj nruab nrab uas siv rau hauv kev tsim cov tshuaj agrochemicals thiab cov tshuaj zoo. Nws qhov kev hloov pauv hauv kev hloov pauv tshuaj ua rau nws muaj txiaj ntsig zoo hauv cov qauv uas xav tau kev tswj hwm meej ntawm cov qauv molecular thiab kev ua haujlwm. Kev Tsim Khoom Ethyl 2-methyl-4,4,4-trifluoroacetoacetate yog tsim los ntawm ntau kauj ruam pib nrog Claisen condensation reaction ntawm ethyl trifluoroacetate nrog methyl acetate, ua raws li esterification nyob rau hauv cov xwm txheej tswj hwm. Cov tshuaj tiv thaiv feem ntau ua tiav nyob rau hauv qhov muaj cov catalyst hauv paus los pab txhawb β-keto ester tsim. Cov txheej txheem purification xws li distillation lossis recrystallization siv los tau txais EMTFA hauv kev huv siab uas haum rau kev siv hauv kev lag luam. Txoj kev tsim khoom yooj yim thiab muaj cov khoom pib pab txhawb rau nws cov nqi-zoo thiab kev siv dav hauv kev tshawb fawb kev kawm thiab cov txheej txheem kev lag luam. Hauv kev xaus lus, ethyl 2-methyl-4,4,4-trifluoroacetoacetate yog ib qho tshuaj sib xyaw ua ke uas muaj ntau yam kev siv tseem ceeb hauv kev tsim cov organic, tshuaj lom neeg, thiab kev tsim cov tshuaj tshwj xeeb. Nws cov khoom siv tshuaj tshwj xeeb, suav nrog kev ruaj khov, kev ua haujlwm, thiab yooj yim ntawm kev tsim, tso nws ua tus neeg ua si tseem ceeb hauv kev txhim kho cov thev naus laus zis thoob plaws ntau yam kev lag luam thiab kev qhuab qhia txog kev tshawb fawb.