Ansamycin CAS: 72559-06-9

Cov tshuaj Ansamycins, xws li rifamycins, feem ntau siv rau hauv kev kho mob los kho ntau yam kab mob bacterial, suav nrog tuberculosis, mob ruas, thiab qee hom kab mob staphylococcal thiab streptococcal. Rifampin, ib hom tshuaj rifamycin uas paub zoo, feem ntau siv ua ib feem ntawm kev kho mob ua ke rau tuberculosis thiab lwm yam kab mob mycobacterial. Lub tshuab ua haujlwm ntawm ansamycins cuam tshuam nrog kev khi rau cov kab mob RNA polymerase, yog li ntawd txwv tsis pub sau ntawv thiab thaum kawg ua rau cov kab mob tuag. Hom kev ua haujlwm tshwj xeeb no ua rau ansamycins muaj txiaj ntsig zoo tiv thaiv ntau yam kab mob Gram-positive thiab Gram-negative. Cov kws kho mob ua tib zoo xav txog cov yam xws li hom kab mob, tus neeg mob keeb kwm kho mob, thiab cov txiaj ntsig ntawm kev kuaj mob thaum sau tshuaj ansamycins. Kev noj tshuaj kom raug, lub sijhawm kho mob, thiab kev saib xyuas cov kev mob tshwm sim yog qhov tseem ceeb rau kev ua kom tau txiaj ntsig zoo tshaj plaws thaum txo qis kev pheej hmoo cuam tshuam nrog kev siv tshuaj tua kab mob. Cov kev mob tshwm sim cuam tshuam nrog ansamycins yuav suav nrog kev cuam tshuam ntawm txoj hnyuv plab, kev ua xua rau lub siab, thiab kev ua xua ntau dhau. Kev saib xyuas tsis tu ncua ntawm kev kuaj mob siab thiab kev soj ntsuam ze rau txhua yam cim ntawm kev tsis zoo yuav pab ua kom muaj kev nyab xeeb thiab siv tau cov tshuaj ansamycins hauv kev kho mob cov kab mob bacterial. Zuag qhia tag nrho, ansamycins yog ib pawg tshuaj tua kab mob muaj txiaj ntsig nrog ntau yam kev siv hauv kev tswj cov kab mob bacterial. Los ntawm kev siv thiab kev saib xyuas kom raug, cov kws kho mob tuaj yeem siv cov khoom tua kab mob ntawm ansamycins los tawm tsam cov kab mob kom zoo thiab txhim kho cov txiaj ntsig ntawm tus neeg mob.