Acetylthiocholine iodide CAS: 1866-15-5

Acetylthiocholine iodide feem ntau yog siv los ua ib qho substrate los ntsuas qhov kev ua haujlwm ntawm cov enzyme acetylcholinesterase (AChE). AChE yog lub luag haujlwm rau kev rhuav tshem cov neurotransmitter acetylcholine hauv lub paj hlwb. Kev ntxiv acetylthiocholine iodide rau hauv cov tshuaj sib xyaw uas muaj AChE ua rau muaj thiocholine thiab acetate.

Qhov kev tshuaj tiv thaiv tuaj yeem pom los ntawm kev ntxiv cov xim qhia lossis fluorometric uas cuam tshuam nrog thiocholine. Tus nqi ntawm cov xim lossis fluorescence tsim yog ncaj qha rau qhov kev ua haujlwm ntawm AChE hauv cov qauv. Qhov no ua rau acetylthiocholine iodide yog ib qho cuab yeej muaj txiaj ntsig rau kev ntsuas AChE kev ua haujlwm hauv ntau yam qauv kab mob, suav nrog cov ntaub so ntswg, cov kab lis kev cai ntawm tes, thiab cov ntshav.

Kev ntsuas AChE kev ua haujlwm siv acetylthiocholine iodide yog siv dav hauv kev tshawb fawb txog cholinergic systems, neurodegenerative disorders, thiab kev raug rau qee yam tshuaj lossis tshuaj uas yuav cuam tshuam rau AChE kev ua haujlwm. Nws kuj tseem siv tau ua lub cuab yeej tshuaj ntsuam xyuas rau kev nrhiav AChE inhibitors, uas yog qhov txaus siab rau kev tsim tshuaj rau cov kab mob xws li Alzheimer's thiab Parkinson's.

Ntxiv rau kev siv rau hauv kev ntsuam xyuas enzymatic, acetylthiocholine iodide kuj tseem siv tau ua lub substrate rau AChE-based biosensors. Cov biosensors no yog tsim los ntes thiab ntsuas qhov muaj qee yam tshuaj uas tuaj yeem tiv thaiv AChE kev ua haujlwm, xws li cov tshuaj tua kab organophosphate lossis cov tshuaj tua kab mob.