Txoj Kev Siv thiab Txoj Kev: Kev sib koom tes, kev sib haum xeeb thiab yeej-yeej
cov khoom

Cov khoom

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS: 86520-63-0

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate yog cov tshuaj sib xyaw uas nquag siv hauv cov tshuaj carbohydrate thiab glycosylation cov tshuaj tiv thaiv.Nws yog ib qho derivative ntawm α-D-galactopyranose, ib hom suab thaj, qhov twg hydroxyl pawg ntawm 2, 3, 4, thiab 6 txoj haujlwm ntawm lub nplhaib galactopyranose yog acetylated.Tsis tas li ntawd, cov anomeric carbon (C1) ntawm cov suab thaj muaj kev tiv thaiv nrog ib pawg trichloroacetimidate, uas ua rau nws muaj zog electrophile thaum lub sij hawm glycosylation cov tshuaj tiv thaiv.

Cov compound feem ntau yog siv los ua tus neeg saib xyuas glycosylating los qhia galactose moieties rau hauv ntau lub molecules, xws li cov proteins, peptides, lossis cov organic molecules me me.Qhov no tuaj yeem ua tiav los ntawm kev ua cov tshuaj no nrog cov nucleophile (piv txwv li, hydroxyl pawg ntawm lub hom phiaj molecule) nyob rau hauv cov xwm txheej tsim nyog.Cov pab pawg trichloroacetimidate pab txhawb kev sib txuas ntawm galactose moiety rau lub hom phiaj molecule, uas ua rau tsim ib daim ntawv cog lus glycosidic.

Cov tshuaj no feem ntau siv rau hauv kev sib txuas ntawm glycoconjugates, glycopeptides, thiab glycolipids.Nws muaj ntau txoj hauv kev thiab ua tau zoo rau kev hloov pauv cov molecules nrog cov galactose residues, uas tuaj yeem cuam tshuam rau ntau yam, suav nrog kev tshawb fawb txog roj ntsha, kev xa tshuaj, lossis kev tsim tshuaj tiv thaiv.


Product Detail

Khoom cim npe

Kev siv thiab cuam tshuam

Glycosylation: Cov compound reacts nrog ntau yam txais cov molecules uas muaj hydroxyl pawg, xws li cawv los yog amines, los tsim glycosidic bonds.Qhov no tso cai rau kev taw qhia ntawm galactose mus rau lub txais molecule, uas ua rau cov synthesis ntawm glycoconjugates, glycopeptides, los yog glycolipids.

Kev tshawb fawb txog biochemical thiab biological: Lub compound pab cov kws tshawb fawb tshawb fawb txog kev ua haujlwm lom neeg thiab kev sib cuam tshuam ntawm galactose-muaj cov molecules.Los ntawm kev xaiv txuas galactose rau cov protein, peptides, lossis lwm yam biomolecules, cov kws tshawb fawb tuaj yeem tshawb xyuas lawv lub luag haujlwm hauv cov txheej txheem ntawm tes, kev sib cuam tshuam ntawm receptor-ligand, thiab kab mob.

Cov tshuab xa tshuaj: Cov khoom sib xyaw tuaj yeem siv los hloov cov tshuaj molecules nrog cov galactose residues, ua kom yooj yim rau cov tshuaj xa mus rau cov ntaub so ntswg lossis cov hlwb.Galactose tuaj yeem ua raws li lub hom phiaj ligand, paub txog cov receptors tshwj xeeb uas tau hais tawm ntawm cov hlwb, tshwj xeeb yog hepatocytes.Los ntawm kev txuas galactose rau cov tshuaj, cov kws tshawb fawb tuaj yeem txhim kho lawv cov kev xaiv thiab kev ua tau zoo hauv kev kho mob.

Kev tsim tshuaj tiv thaiv: Galactose-muaj cov molecules ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob, raws li lawv tau lees paub los ntawm lectins tam sim no ntawm lub cev tiv thaiv kab mob.Los ntawm conjugating antigens nrog galactose moieties siv qhov sib xyaw no, cov kws tshawb fawb tuaj yeem txhim kho lub cev tiv thaiv kab mob thiab tsim cov tshuaj tiv thaiv zoo dua.

Chemical synthesis: Lub compound tuaj yeem ua haujlwm hauv ntau cov tshuaj syntheses uas yuav tsum tau hloov kho galactose.Qhov no suav nrog kev npaj cov txheej txheem carbohydrate nyuaj, oligosaccharides, lossis glycomimetics, uas tuaj yeem siv ntxiv hauv tshuaj chemistry lossis ua cov cuab yeej tshawb fawb.

Khoom qauv

1.1
2

Cov khoom ntim:

6892-68-8-3

Cov ntaub ntawv ntxiv:

Kev sib xyaw C16H20Cl3NO10
Assay 99%
Qhov tshwm sim Dawb hmoov
CAS Nr. 86520-63-0
Ntim Me me thiab bulk
Txee lub neej 2 xyoo
Cia Khaws rau hauv qhov chaw txias thiab qhuav
Daim ntawv pov thawj ISO.

 


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