1-Butanone, 2-(dimethylamino)-2-(4-methylphenyl)methyl-1-4-(4-morpholinyl)phenyl- CAS: 119344-86-4

Qhov muaj cov pawg dimethylamino tso cai rau kev txhim kho solubility thiab kev sib cuam tshuam nrog cov receptors lossis enzymes hauv cov kab ke hauv lub cev. Kev sib xyaw ua ke ntawm 4-methylphenyl thiab morpholinyl pawg muab cov yam ntxwv ntxiv uas tuaj yeem cuam tshuam rau cov khoom siv pharmacological. Cov yam ntxwv no pab txhawb rau lub peev xwm ntawm cov khoom siv ua cov tshuaj lead lossis nruab nrab hauv kev tshawb pom tshuaj. 1-Butanone, 2-(dimethylamino)-2-(4-methylphenyl)methyl-1-4-(4-morpholinyl)phenyl- pom cov ntawv thov hauv kev kho mob vim nws muaj peev xwm cuam tshuam nrog cov protein lossis receptors tshwj xeeb. Nws tuaj yeem siv ua cov khoom siv pib rau kev tsim cov analogs lossis derivatives nrog kev txhim kho potency, selectivity, lossis pharmacokinetic zog. Cov pab pawg ua haujlwm sib txawv ntawm cov tshuaj muab cov sijhawm rau kev hloov kho ntxiv thiab kev ua kom zoo dua ntawm cov haujlwm biological xav tau. Ntxiv nrog rau nws cov peev xwm tshuaj, cov tshuaj no kuj tseem yuav pom kev siv hauv lwm qhov chaw tshawb fawb. Nws cov qauv nyuaj ua rau nws tsim nyog rau kev tshawb fawb uas cuam tshuam nrog kev sib raug zoo ntawm cov qauv-kev ua ub no, kev ua qauv molecular, thiab kev suav lej chemistry. Los ntawm kev nkag siab txog kev sib cuam tshuam ntawm cov tshuaj no thiab nws cov molecules lub hom phiaj, cov kws tshawb fawb tuaj yeem nkag siab txog cov txheej txheem ua haujlwm thiab tsim cov tswv yim tshiab rau kev kho mob. Ntxiv mus, 1-Butanone, 2-(dimethylamino)-2-(4-methylphenyl)methyl-1-4-(4-morpholinyl)phenyl- tej zaum yuav muaj kev siv dhau ntawm cov tshuaj kho mob. Nws cov yam ntxwv sib txawv ua rau nws yog ib qho tshuaj lom neeg nthuav rau kev tshawb fawb txog cov ntaub ntawv, tshwj xeeb tshaj yog hauv kev tsim cov ntaub ntawv ua haujlwm lossis polymers. Kev qhia txog ntau yam kev ua haujlwm ntawm cov pab pawg hauv ib lub molecule qhib qhov ua tau rau cov ntaub ntawv ua tshwj xeeb nrog cov khoom tshwj xeeb, xws li cov yam ntxwv pom, hluav taws xob, lossis cov yam ntxwv kho tshuab. Hauv kev xaus, 1-Butanone, 2-(dimethylamino)-2-(4-methylphenyl)methyl-1-4-(4-morpholinyl)phenyl- yog ib qho tshuaj lom neeg uas muaj peev xwm tseem ceeb hauv kev kho mob tshuaj, kev tshawb pom tshuaj, thiab kev tshawb fawb txog cov ntaub ntawv. Nws cov qauv nyuaj, sib xyaw ua ke ntau pawg ua haujlwm, muab kev hloov pauv thiab lub sijhawm rau kev hloov kho ntxiv thiab kev ua kom zoo dua ntawm cov khoom xav tau. Nrog nws cov ntawv thov sib txawv, cov tshuaj no sawv cev rau ib qho cuab yeej muaj txiaj ntsig rau cov kws tshawb fawb hauv lawv txoj kev tshawb nrhiav cov tshuaj kho mob tshiab, cov ntaub ntawv ua haujlwm, thiab kev nce qib ntawm kev tshawb fawb.