α-Galactosidase CAS: 9025-35-8

α-galactosidase(α-galactosidase, α-gal, EC 3.2.1.22) yog ib qho exoglycosidase uas ua rau lub hydrolysis ntawm α-galactosidic bonds. Vim tias nws tuaj yeem rhuav tshem melibiose, nws tseem hu ua melibiase, uas ua rau lub hydrolysis ntawm α-galactosidic bonds. Qhov feature no ua rau nws muaj txiaj ntsig zoo rau kev txhim kho thiab tshem tawm cov khoom tsis zoo hauv cov khoom noj pub thiab cov khoom noj uas muaj taum pauv. Tsis tas li ntawd, nws tuaj yeem paub txog kev hloov pauv hom ntshav B → O hauv kev kho mob, npaj cov ntshav thoob ntiaj teb, thiab ua lub luag haujlwm tseem ceeb hauv kev kho mob hloov pauv enzyme ntawm Fabry kab mob. α-galactosidase kuj tseem tuaj yeem ua rau cov polysaccharides nyuaj, glycoproteins thiab glycosphingoses uas muaj α-galactosidic bonds. Qee qhov α-galactosidases kuj tseem tuaj yeem transgalactosylate thaum qhov concentration ntawm substrate yog nplua nuj heev, thiab qhov feature no tuaj yeem siv rau kev tsim cov oligosaccharides thiab kev npaj cov cyclodextrin derivatives. Kev tsim cov neutrophil lossis pH-ruaj khov α-galactosidase thiab kev tshawb nrhiav cov kab mob me me lossis cov nroj tsuag uas muaj cov enzyme ntau tau dhau los ua qhov chaw tshawb fawb kub hauv xyoo tas los no. Ntau cov α-galactosidases uas tiv taus cua sov kuj tau maj mam ua rau muaj kev txaus siab ntawm cov kws tshawb fawb vim lawv qhov tshwj xeeb, xav tias yuav siv lawv qhov kev ruaj khov thermal los ua si ntau dua hauv kev lag luam, thiab los qhia ntau yam kev siv hauv kev siv thev naus laus zis, thev naus laus zis thiab tshuaj.