Simvastatin CAS: 79902-63-9 Chaw tsim tshuaj paus

Simvastatin yog semi-synthetic, me ntsis hydrophobic, analogue ntawm lovastatin.Zoo li lovastatin, simvastatin yog ib qho tshwj xeeb inhibitor ntawm HMG-CoA reductase thiab tau siv kho kom txo qis LDL roj cholesterol.Tsis ntev los no, statins tau dhau los ua qhov tseem ceeb ntawm biochemical soj ntsuam hauv cell biology.Lawv txoj kev koom tes hauv ntau qhov xwm txheej tuaj yeem cuam tshuam nrog lawv qhov kev ua haujlwm tseem ceeb, txawm li cas los xij, cov txheej txheem ntawm kev ua ntawm ntau lwm yam cuam tshuam tsis tshua pom. rau mevalonate, ib kauj ruam thaum ntxov hauv cov roj cholesterol biosynthesis.Nws yog siv rau hauv kev kho mob ntawm hypercholesterolemia, vim nws txo qis lipoproteins tsawg thiab triglycerides, thiab nce siab lipoprotein ntau ntau.