Mirabegron CAS: 223673-61-8 Chaw tsim tshuaj paus

Mirabegron yog siv rau kev kho mob ceev, tso zis ntau zaus, thiab tso zis tso zis tso quav nrog rau lub zais zis ntau dhau (OAB).Mirabegron yog tsim los ntawm kev sib txuas ntawm 4-nitrophenethyl amine rau (R)-2-hydroxy-2-phenylacetic acid.Qhov tshwm sim amide yog txo mus rau ib qho amine.Cov pab pawg nitro raug txo qis thiab cov txiaj ntsig tau ua ke rau 2-(2-aminothiazol-4-yl) acetic acid muab mirabegron.

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Mirabegron yog ib qho active β3-adrenoceptor agonist tam sim no nyob rau hauv txoj kev loj hlob los ntawm Astellas Pharma rau kev kho mob ntawm overactive zais zis (OAB).Cov tshuaj yog ib tug nanomolar EC50 antagonist tawm tsam tib neeg β3-AR biochemical kev soj ntsuam nrog zoo xaiv tshaj b1- thiab β2-ARs.Mirabegron qhia txog lub tswv yim tshiab los ntawm kev tsom mus rau β3-AR rau lub zais zis los pab tswj OAB cov tsos mob xws li nce zis ceev thiab zaus thiab ceev ceev incontinence.Txawm li cas los xij, mirabegron yog cytochrome P450 2D6 inhibitor, thiab nws ua rau muaj kev txhawj xeeb rau kev siv tshuaj yeeb-tshuaj nrog kev tswj hwm ntawm lwm cov cytochrome P450 2D6 substrates.

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Kev sib xyaw	C21H24N4O2S
Assay	99%
Qhov tshwm sim	Dawb rau Pale Yellow hmoov
CAS Nr.	223673-61-8
Ntim	25 KG
Txee lub neej	2 xyoo
Cia	Khaws rau hauv qhov chaw txias thiab qhuav
Daim ntawv pov thawj	ISO.