2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS: 86520-63-0

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate yog ib qho tshuaj lom neeg uas feem ntau siv rau hauv cov tshuaj carbohydrate thiab glycosylation reactions. Nws yog ib qho derivative ntawm α-D-galactopyranose, ib hom suab thaj, qhov twg cov hydroxyl pawg ntawm 2, 3, 4, thiab 6 txoj haujlwm ntawm lub nplhaib galactopyranose yog acetylated. Tsis tas li ntawd, cov pa roj carbon anomeric (C1) ntawm cov suab thaj yog tiv thaiv nrog ib pawg trichloroacetimidate, uas ua rau nws yog ib qho electrophile muaj zog thaum lub sijhawm glycosylation reactions.

Cov tshuaj no feem ntau siv los ua tus neeg sawv cev glycosylating los qhia cov galactose moieties rau hauv ntau yam molecules, xws li cov protein, peptides, lossis cov organic molecules me me. Qhov no tuaj yeem ua tiav los ntawm kev cuam tshuam cov tshuaj no nrog nucleophile (piv txwv li, hydroxyl pawg ntawm lub hom phiaj molecule) nyob rau hauv cov xwm txheej tsim nyog. Pawg trichloroacetimidate pab txhawb kev txuas ntawm galactose moiety rau lub hom phiaj molecule, ua rau muaj kev tsim ntawm glycosidic bond.

Cov tshuaj no feem ntau siv rau hauv kev tsim cov glycoconjugates, glycopeptides, thiab glycolipids. Nws muab ib txoj hauv kev ua tau zoo thiab siv tau zoo rau kev hloov kho cov molecules nrog galactose residues, uas tuaj yeem cuam tshuam rau ntau qhov chaw, suav nrog kev tshawb fawb txog tsiaj txhu, kev xa tshuaj, lossis kev tsim tshuaj tiv thaiv kab mob.

Txiav txim los yog Thov Kev Hais Nqe

Cov Lus Qhia Txog Khoom

Cov Cim Npe Khoom

Daim Ntawv Thov thiab Cov Nyhuv

Glycosylation: Cov tshuaj no cuam tshuam nrog ntau yam khoom siv uas muaj cov pab pawg hydroxyl, xws li cawv lossis amines, los tsim cov glycosidic bonds. Qhov no tso cai rau kev qhia txog galactose rau ntawm cov khoom siv uas txais, ua rau muaj kev sib xyaw ntawm glycoconjugates, glycopeptides, lossis glycolipids.

Kev kawm txog biochemical thiab biological: Cov tshuaj no pab cov kws tshawb fawb kawm txog kev ua haujlwm ntawm cov kab mob thiab kev sib cuam tshuam ntawm cov molecule uas muaj galactose. Los ntawm kev xaiv txuas galactose rau cov protein, peptides, lossis lwm yam biomolecules, cov kws tshawb fawb tuaj yeem tshawb xyuas lawv lub luag haujlwm hauv cov txheej txheem cellular, kev sib cuam tshuam ntawm receptor-ligand, thiab cov txheej txheem kab mob.

Cov txheej txheem xa tshuaj: Cov tshuaj no siv tau los hloov cov tshuaj nrog cov galactose residues, pab txhawb kev xa tshuaj mus rau cov nqaij lossis cov hlwb tshwj xeeb. Galactose tuaj yeem ua haujlwm ua cov ligand tsom, lees paub cov receptors tshwj xeeb uas tau qhia tawm ntawm qhov chaw ntawm cov hlwb, tshwj xeeb tshaj yog hepatocytes. Los ntawm kev txuas galactose rau cov tshuaj, cov kws tshawb fawb tuaj yeem txhim kho lawv txoj kev xaiv thiab kev ua haujlwm zoo hauv kev kho mob tsom.

Kev tsim tshuaj tiv thaiv kab mob: Cov tshuaj uas muaj galactose ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob, vim tias lawv raug lees paub los ntawm lectins uas muaj nyob rau ntawm cov hlwb tiv thaiv kab mob. Los ntawm kev sib txuas cov antigens nrog galactose moieties siv cov tshuaj no, cov kws tshawb fawb tuaj yeem txhim kho kev tiv thaiv kab mob thiab tsim cov tshuaj tiv thaiv kab mob zoo dua.

Kev tsim cov tshuaj lom neeg: Cov tshuaj no tuaj yeem siv rau hauv ntau yam kev tsim cov tshuaj uas xav tau kev hloov kho galactose. Qhov no suav nrog kev npaj cov qauv carbohydrate nyuaj, oligosaccharides, lossis glycomimetics, uas tuaj yeem siv ntxiv rau hauv kev kho mob tshuaj lossis ua cov cuab yeej tshawb fawb.

Qauv Khoom

Khoom Ntim:

Cov Lus Qhia Ntxiv:

Kev sau ua ke	C16H20Cl3NO10
Kev Ntsuas	99%
Qhov tsos	Hmoov dawb
CAS Nr.	86520-63-0
Ntim khoom	Me me thiab ntau
Lub Neej Txee	2 xyoos
Kev Khaws Cia	Khaws cia rau qhov chaw txias thiab qhuav
Daim Ntawv Pov Thawj	ISO.