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Cov khoom

2'-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM ntsev CAS: 76204-02-9

2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium ntsev yog ib qho tshuaj lom neeg siv hauv kev kuaj mob thiab kev tshawb fawb.Nws yog fluorescently sau npe derivative ntawm sialic acid, ib hom carbohydrate molecule pom nyob rau saum npoo ntawm cov hlwb.

Cov tshuaj no yog siv los ua ib qho substrate rau cov enzymes hu ua neuraminidases, uas ua rau tshem tawm sialic acid residues ntawm glycoproteins thiab glycolipids.Thaum cov enzymes no ua rau 2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium ntsev, nws tso cov khoom fluorescent hu ua 4-methylumbelliferone.

Cov fluorescence tsim los ntawm cov compound tuaj yeem ntsuas thiab ntsuas, muab cov ntaub ntawv ntawm kev ua haujlwm ntawm neuraminidase enzymes.Qhov no yog tshwj xeeb tshaj yog pab tau nyob rau hauv txoj kev tshawb no ntawm ntau yam kab mob thiab tej yam kev mob txuam nrog aberrant sialic acid metabolism.

Cov tshuaj kuj tseem siv rau kev kuaj mob, xws li hauv kev tshawb nrhiav cov kab mob kis uas cuam tshuam nrog kev ua haujlwm ntawm neuraminidase.Nyob rau hauv cov kev ntsuam xyuas no, cov compound yog siv los txheeb xyuas qhov muaj cov kab mob tshwj xeeb lossis tshuaj xyuas cov txiaj ntsig ntawm neuraminidase inhibitors hauv kev kho tshuaj tiv thaiv kab mob.


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Neuraminidase Activity Assay: Cov tshuaj no feem ntau siv los ntsuas cov haujlwm ntawm neuraminidase enzymes hauv cov qauv lom neeg.Los ntawm kev saib xyuas cov fluorescence generated, cov kws tshawb fawb tuaj yeem txiav txim siab txog qib ntawm neuraminidase kev ua haujlwm, uas tuaj yeem pab hauv kev kawm txog ntau yam kab mob thiab kev mob.

Kev kuaj kab mob kis kab mob: Ntau yam kab mob kis, suav nrog mob khaub thuas, koom nrog kev ua haujlwm ntawm neuraminidase.Cov tshuaj no tuaj yeem siv los txheeb xyuas thiab ntsuas qhov muaj cov kab mob tshwj xeeb los ntawm kev ntsuas kev ua haujlwm fluorescent.Nws yog ib qho tseem ceeb tshwj xeeb hauv kev ntsuam xyuas cov txiaj ntsig ntawm neuraminidase inhibitors hauv kev kho mob antiviral.

Glycosylation Analysis: Sialic acid yog ib qho tseem ceeb ntawm glycoproteins thiab glycolipids.Los ntawm kev koom nrog 2'-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium ntsev rau hauv kev sim, cov kws tshawb fawb tuaj yeem nkag siab txog sialic acid metabolism, glycosylation qauv, thiab cov txheej txheem physiological.

Kev Tshawb Nrhiav Tshuaj: Neuraminidase inhibitors yog ib chav kawm ntawm cov tshuaj siv los kho cov kab mob kis.Cov tshuaj no tuaj yeem siv rau hauv kev tshawb nrhiav tshuaj, pab cov kws tshawb fawb txheeb xyuas thiab ntsuas cov peev xwm inhibitors ntawm neuraminidase kev ua haujlwm.

 

Cov khoom ntim:

6892-68-8-3

Cov ntaub ntawv ntxiv:

Kev sib xyaw C21H26NaO11
Assay 99%
Qhov tshwm sim Dawb hmoov
CAS Nr. 76204-02-9
Ntim Me me thiab bulk
Txee lub neej 2 xyoo
Cia Khaws rau hauv qhov chaw txias thiab qhuav
Daim ntawv pov thawj ISO.

 


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